X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women

X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women

Abstract The incidence of pituitary adrenocorticotropic hormone (ACTH)-secreting PitNETs, commonly known as ACTH PitNETs, is significantly higher in females; however, the underlying causes for this gender disparity remain unclear. In this study, we analyzed the expression of deubiquitinating enzymes...

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Bibliographic Details
Main Authors: Tao Zhang, Yanting Liu, Fang Liu, Kaiyu Guo, Runhua Tang, Jingwei Ye, Li Xue, Zhipeng Su, Zhe Bao Wu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Acta Neuropathologica Communications
Subjects:
Cushing’s disease
Sex differences
USP11
TPIT
Adrenocorticotrophic hormone
Online Access:https://doi.org/10.1186/s40478-025-01938-9
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