Trans-differentiation of Jdp2-depleted Gaba-receptor-positive cerebellar granule cells to Purkinje cells

Trans-differentiation of Jdp2-depleted Gaba-receptor-positive cerebellar granule cells to Purkinje cells

Abstract The Jun dimerization protein (Jdp2) gene is active in mouse cerebellar granule cells and its protein product plays a crucial role in the formation of the cerebellum lobes through programmed cell death. However, the role of Jdp2 in cellular differentiation and pluripotency in the cerebellum,...

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Main Authors: Chia-Chen Ku, Jia-Bin Pan, Kenly Wuputra, Wen-Li Hsu, Kohsuke Kato, Michiya Noguchi, Yukio Nakamura, Shigeo Saito, Cheng-Yu Tsai, Ying-Chu Lin, Deng-Chyang Wu, Chang-Shen Lin, Kazunari K. Yokoyama
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02262-2
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