Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT
Purpose: Using a fully automated multitask deep learning method, which enabled simultaneous segmentation and quantification of all major anterior segment structures with swept-source optical coherence tomography (SS-OCT), we aimed to investigate the three-dimensional (3D) alterations in iris morphol...
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Elsevier
2025-01-01
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024175731 |
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| author | Zhengwei Zhang Shuimiao Chang Kaiwen Li Jinhan Yao Zhao Wang Jiewei Liu Lin Jiang Feiyan Chai Xiaogang Wang |
| author_facet | Zhengwei Zhang Shuimiao Chang Kaiwen Li Jinhan Yao Zhao Wang Jiewei Liu Lin Jiang Feiyan Chai Xiaogang Wang |
| author_sort | Zhengwei Zhang |
| collection | DOAJ |
| description | Purpose: Using a fully automated multitask deep learning method, which enabled simultaneous segmentation and quantification of all major anterior segment structures with swept-source optical coherence tomography (SS-OCT), we aimed to investigate the three-dimensional (3D) alterations in iris morphology before and after implantable collamer lens (ICL) surgery. Methods: All enrolled patients underwent anterior segment SS-OCT (ANTERION) within one week before and after ICL surgery. A multitask network automatically performed iris SS-OCT image segmentation and quantitative measurements of 3D iris morphology (iris thickness and volume of the inner 1-mm annular area and the outer 1–2-mm annular area, iris curvature [I-Curve], and iris smooth index [SI]). Results: Forty-six eyes of 27 patients (average age, 26.0 ± 5.3 years) were included in the final data analysis. The spherical equivalent ranged from −15.75 to −4.00 diopters (D). The mean ICL vault values were 537.92 ± 161.69 μm, which positively and significantly correlated with the pre- (r = 0.333, P = 0.024) and postoperative (r = 0.351, P = 0.017) anterior chamber depth (ACD). The mean pupil diameter significantly decreased, whereas both ACD and lens thickness significantly increased postoperatively. The iris thickness, iris volume of the inner 1-mm annular area and the outer 1–2-mm annular area, and SI decreased significantly within one week after ICL implantation. All mean values of the I-Curve increased dramatically postoperatively. Conclusion: Iris morphology, ACD, and lens thickness were significantly altered after ICL implantation. |
| format | Article |
| id | doaj-art-506a2da739a94e46862d96bce9efb7f2 |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-506a2da739a94e46862d96bce9efb7f22025-01-17T04:51:35ZengElsevierHeliyon2405-84402025-01-01111e41542Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCTZhengwei Zhang0Shuimiao Chang1Kaiwen Li2Jinhan Yao3Zhao Wang4Jiewei Liu5Lin Jiang6Feiyan Chai7Xiaogang Wang8Department of Ophthalmology, Wuxi No.2 People's Hospital, Affiliated Wuxi Clinical College of Nantong University, Wuxi, Jiangsu, 214002, China; Department of Ophthalmology, Jiangnan University Medical Centre, Wuxi, Jiangsu, 214002, ChinaShanxi Medical University, Taiyuan, Shanxi, ChinaSchool of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610054, ChinaShanxi Medical University, Taiyuan, Shanxi, ChinaSchool of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610054, ChinaDepartment of Cataract, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, 030001, ChinaDepartment of Cataract, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, 030001, ChinaDepartment of Cataract, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, 030001, ChinaDepartment of Cataract, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, 030001, China; Corresponding author. No. 100 Fudong Street, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Shanxi, 030002, China.Purpose: Using a fully automated multitask deep learning method, which enabled simultaneous segmentation and quantification of all major anterior segment structures with swept-source optical coherence tomography (SS-OCT), we aimed to investigate the three-dimensional (3D) alterations in iris morphology before and after implantable collamer lens (ICL) surgery. Methods: All enrolled patients underwent anterior segment SS-OCT (ANTERION) within one week before and after ICL surgery. A multitask network automatically performed iris SS-OCT image segmentation and quantitative measurements of 3D iris morphology (iris thickness and volume of the inner 1-mm annular area and the outer 1–2-mm annular area, iris curvature [I-Curve], and iris smooth index [SI]). Results: Forty-six eyes of 27 patients (average age, 26.0 ± 5.3 years) were included in the final data analysis. The spherical equivalent ranged from −15.75 to −4.00 diopters (D). The mean ICL vault values were 537.92 ± 161.69 μm, which positively and significantly correlated with the pre- (r = 0.333, P = 0.024) and postoperative (r = 0.351, P = 0.017) anterior chamber depth (ACD). The mean pupil diameter significantly decreased, whereas both ACD and lens thickness significantly increased postoperatively. The iris thickness, iris volume of the inner 1-mm annular area and the outer 1–2-mm annular area, and SI decreased significantly within one week after ICL implantation. All mean values of the I-Curve increased dramatically postoperatively. Conclusion: Iris morphology, ACD, and lens thickness were significantly altered after ICL implantation.http://www.sciencedirect.com/science/article/pii/S2405844024175731Implantable collamer lensIris morphologyICL vaultDeep learningSwept-source optical coherence tomography |
| spellingShingle | Zhengwei Zhang Shuimiao Chang Kaiwen Li Jinhan Yao Zhao Wang Jiewei Liu Lin Jiang Feiyan Chai Xiaogang Wang Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT Heliyon Implantable collamer lens Iris morphology ICL vault Deep learning Swept-source optical coherence tomography |
| title | Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT |
| title_full | Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT |
| title_fullStr | Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT |
| title_full_unstemmed | Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT |
| title_short | Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT |
| title_sort | investigation of 3d iris morphology early alteration after implantable collamer lens implantation by using ss oct |
| topic | Implantable collamer lens Iris morphology ICL vault Deep learning Swept-source optical coherence tomography |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024175731 |
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