Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT
Purpose: Using a fully automated multitask deep learning method, which enabled simultaneous segmentation and quantification of all major anterior segment structures with swept-source optical coherence tomography (SS-OCT), we aimed to investigate the three-dimensional (3D) alterations in iris morphol...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024175731 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Purpose: Using a fully automated multitask deep learning method, which enabled simultaneous segmentation and quantification of all major anterior segment structures with swept-source optical coherence tomography (SS-OCT), we aimed to investigate the three-dimensional (3D) alterations in iris morphology before and after implantable collamer lens (ICL) surgery. Methods: All enrolled patients underwent anterior segment SS-OCT (ANTERION) within one week before and after ICL surgery. A multitask network automatically performed iris SS-OCT image segmentation and quantitative measurements of 3D iris morphology (iris thickness and volume of the inner 1-mm annular area and the outer 1–2-mm annular area, iris curvature [I-Curve], and iris smooth index [SI]). Results: Forty-six eyes of 27 patients (average age, 26.0 ± 5.3 years) were included in the final data analysis. The spherical equivalent ranged from −15.75 to −4.00 diopters (D). The mean ICL vault values were 537.92 ± 161.69 μm, which positively and significantly correlated with the pre- (r = 0.333, P = 0.024) and postoperative (r = 0.351, P = 0.017) anterior chamber depth (ACD). The mean pupil diameter significantly decreased, whereas both ACD and lens thickness significantly increased postoperatively. The iris thickness, iris volume of the inner 1-mm annular area and the outer 1–2-mm annular area, and SI decreased significantly within one week after ICL implantation. All mean values of the I-Curve increased dramatically postoperatively. Conclusion: Iris morphology, ACD, and lens thickness were significantly altered after ICL implantation. |
|---|---|
| ISSN: | 2405-8440 |