Per- and Polyfluoroalkyl Substances (PFASs) in Market Meats from Guangzhou, China: Age-Specific Dietary Exposure and Threshold Exceedance Risks
Per- and polyfluoroalkyl substances (PFASs), known for their environmental persistence and adverse health effects, pose an elevated risk to vulnerable populations through dietary exposure. Yet, there is limited research on PFAS concentrations in market basket meats and offal from Guangzhou, China. W...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
|
| Series: | Journal of Food Protection |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0362028X25001449 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849227002376093696 |
|---|---|
| author | Yuting Qin Yuhua Zhang Hongfeng Zhang Yan Li Zhijun Bai Yanyan Wang Lili Huang Weiwei Zhang |
| author_facet | Yuting Qin Yuhua Zhang Hongfeng Zhang Yan Li Zhijun Bai Yanyan Wang Lili Huang Weiwei Zhang |
| author_sort | Yuting Qin |
| collection | DOAJ |
| description | Per- and polyfluoroalkyl substances (PFASs), known for their environmental persistence and adverse health effects, pose an elevated risk to vulnerable populations through dietary exposure. Yet, there is limited research on PFAS concentrations in market basket meats and offal from Guangzhou, China. We examined the distribution of 16 PFAS in 166 market basket samples (beef, pork, and offal (pork liver)) from Guangzhou. Age-specific dietary exposure and related health risk were assessed for 3–6-year-old children, 7–17-year-old adolescents, adults, and seniors, integrating local food consumption data and probabilistic risk models. The results demonstrated a variable distribution of PFAS based on food species, with offal exhibiting the highest level of contamination (mean Ʃ16PFAS: 6.209 ng·g−1). Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) were identified as the most predominant compounds contributing to dietary exposure of total PFAS. For the estimated weekly intake (EWI) of Ʃ4PFAS [PFOA, PFOS, Perfluorononanoic acid (PFNA), and Perfluorohexanesulfonic acid (PFHxS)] from meats and offal, the average EWI ranged from 3.252 to 5.710 ng·kg−1 body weight (bw) per week in four age groups. The probability of exceeding tolerable weekly intake (4.4 ng·kg−1 bw per week) is 51% in children, 45% in adolescents, and 39% in both adults and seniors. Offal was identified as the predominant source of the total PFAS exposure. This study provides the first insights into the age-specific health risk of PFAS from market meats and offal from Guangzhou, highlighting the urgent need for further research to establish safety benchmarks or consumption advisory values for these compounds in the Chinese diet. |
| format | Article |
| id | doaj-art-4ff922bae2e14eb6bd8edf306081d30d |
| institution | Kabale University |
| issn | 0362-028X |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Food Protection |
| spelling | doaj-art-4ff922bae2e14eb6bd8edf306081d30d2025-08-24T05:11:23ZengElsevierJournal of Food Protection0362-028X2025-09-01881010059210.1016/j.jfp.2025.100592Per- and Polyfluoroalkyl Substances (PFASs) in Market Meats from Guangzhou, China: Age-Specific Dietary Exposure and Threshold Exceedance RisksYuting Qin0Yuhua Zhang1Hongfeng Zhang2Yan Li3Zhijun Bai4Yanyan Wang5Lili Huang6Weiwei Zhang7Guangzhou Center for Disease Control and Prevention, 510440 Guangzhou, ChinaGuangzhou Center for Disease Control and Prevention, 510440 Guangzhou, ChinaGuangzhou Center for Disease Control and Prevention, 510440 Guangzhou, ChinaGuangzhou Center for Disease Control and Prevention, 510440 Guangzhou, ChinaGuangzhou Center for Disease Control and Prevention, 510440 Guangzhou, ChinaGuangzhou Center for Disease Control and Prevention, 510440 Guangzhou, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Guangdong Pharmaceutical University & Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, ChinaGuangzhou Center for Disease Control and Prevention, 510440 Guangzhou, China; Corresponding author.Per- and polyfluoroalkyl substances (PFASs), known for their environmental persistence and adverse health effects, pose an elevated risk to vulnerable populations through dietary exposure. Yet, there is limited research on PFAS concentrations in market basket meats and offal from Guangzhou, China. We examined the distribution of 16 PFAS in 166 market basket samples (beef, pork, and offal (pork liver)) from Guangzhou. Age-specific dietary exposure and related health risk were assessed for 3–6-year-old children, 7–17-year-old adolescents, adults, and seniors, integrating local food consumption data and probabilistic risk models. The results demonstrated a variable distribution of PFAS based on food species, with offal exhibiting the highest level of contamination (mean Ʃ16PFAS: 6.209 ng·g−1). Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) were identified as the most predominant compounds contributing to dietary exposure of total PFAS. For the estimated weekly intake (EWI) of Ʃ4PFAS [PFOA, PFOS, Perfluorononanoic acid (PFNA), and Perfluorohexanesulfonic acid (PFHxS)] from meats and offal, the average EWI ranged from 3.252 to 5.710 ng·kg−1 body weight (bw) per week in four age groups. The probability of exceeding tolerable weekly intake (4.4 ng·kg−1 bw per week) is 51% in children, 45% in adolescents, and 39% in both adults and seniors. Offal was identified as the predominant source of the total PFAS exposure. This study provides the first insights into the age-specific health risk of PFAS from market meats and offal from Guangzhou, highlighting the urgent need for further research to establish safety benchmarks or consumption advisory values for these compounds in the Chinese diet.http://www.sciencedirect.com/science/article/pii/S0362028X25001449Dietary exposureMeatsOffalPer- and polyfluoroalkyl substancesResidue distributionRisk assessment |
| spellingShingle | Yuting Qin Yuhua Zhang Hongfeng Zhang Yan Li Zhijun Bai Yanyan Wang Lili Huang Weiwei Zhang Per- and Polyfluoroalkyl Substances (PFASs) in Market Meats from Guangzhou, China: Age-Specific Dietary Exposure and Threshold Exceedance Risks Journal of Food Protection Dietary exposure Meats Offal Per- and polyfluoroalkyl substances Residue distribution Risk assessment |
| title | Per- and Polyfluoroalkyl Substances (PFASs) in Market Meats from Guangzhou, China: Age-Specific Dietary Exposure and Threshold Exceedance Risks |
| title_full | Per- and Polyfluoroalkyl Substances (PFASs) in Market Meats from Guangzhou, China: Age-Specific Dietary Exposure and Threshold Exceedance Risks |
| title_fullStr | Per- and Polyfluoroalkyl Substances (PFASs) in Market Meats from Guangzhou, China: Age-Specific Dietary Exposure and Threshold Exceedance Risks |
| title_full_unstemmed | Per- and Polyfluoroalkyl Substances (PFASs) in Market Meats from Guangzhou, China: Age-Specific Dietary Exposure and Threshold Exceedance Risks |
| title_short | Per- and Polyfluoroalkyl Substances (PFASs) in Market Meats from Guangzhou, China: Age-Specific Dietary Exposure and Threshold Exceedance Risks |
| title_sort | per and polyfluoroalkyl substances pfass in market meats from guangzhou china age specific dietary exposure and threshold exceedance risks |
| topic | Dietary exposure Meats Offal Per- and polyfluoroalkyl substances Residue distribution Risk assessment |
| url | http://www.sciencedirect.com/science/article/pii/S0362028X25001449 |
| work_keys_str_mv | AT yutingqin perandpolyfluoroalkylsubstancespfassinmarketmeatsfromguangzhouchinaagespecificdietaryexposureandthresholdexceedancerisks AT yuhuazhang perandpolyfluoroalkylsubstancespfassinmarketmeatsfromguangzhouchinaagespecificdietaryexposureandthresholdexceedancerisks AT hongfengzhang perandpolyfluoroalkylsubstancespfassinmarketmeatsfromguangzhouchinaagespecificdietaryexposureandthresholdexceedancerisks AT yanli perandpolyfluoroalkylsubstancespfassinmarketmeatsfromguangzhouchinaagespecificdietaryexposureandthresholdexceedancerisks AT zhijunbai perandpolyfluoroalkylsubstancespfassinmarketmeatsfromguangzhouchinaagespecificdietaryexposureandthresholdexceedancerisks AT yanyanwang perandpolyfluoroalkylsubstancespfassinmarketmeatsfromguangzhouchinaagespecificdietaryexposureandthresholdexceedancerisks AT lilihuang perandpolyfluoroalkylsubstancespfassinmarketmeatsfromguangzhouchinaagespecificdietaryexposureandthresholdexceedancerisks AT weiweizhang perandpolyfluoroalkylsubstancespfassinmarketmeatsfromguangzhouchinaagespecificdietaryexposureandthresholdexceedancerisks |