Small Intestinal Bacterial Overgrowth Syndrome: New Clinical Insights for Multimorbid and High-Risk Patients
Introduction Small Intestinal Bacterial Overgrowth (SIBO) syndrome has emerged as a significant clinical issue associated with various gastrointestinal and systemic conditions. The syndrome is characterized by an excessive proliferation of bacteria in the small intestine, leading to symptoms such a...
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Nicolaus Copernicus University in Toruń
2024-12-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/56729 |
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| author | Krzysztof Nowakowski Zuzanna Mularczyk Magdalena Reclik Piotr Oleksy Maciej Tenderenda |
| author_facet | Krzysztof Nowakowski Zuzanna Mularczyk Magdalena Reclik Piotr Oleksy Maciej Tenderenda |
| author_sort | Krzysztof Nowakowski |
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Introduction
Small Intestinal Bacterial Overgrowth (SIBO) syndrome has emerged as a significant clinical issue associated with various gastrointestinal and systemic conditions. The syndrome is characterized by an excessive proliferation of bacteria in the small intestine, leading to symptoms such as bloating, diarrhoea, constipation, abdominal pain, and malabsorption. These symptoms contribute to a decline in patients' quality of life, malnutrition, and nutritional deficiencies. Despite its clinical relevance, SIBO remains underdiagnosed in routine practice.
Purpose of Research
This study aims to review the current understanding of the pathophysiology, clinical presentation, diagnostic approaches, and treatment options for SIBO, with a focus on improving clinical recognition and management.
Materials and Methods
A comprehensive literature review was conducted, analyzing 31 articles sourced from PubMed, Scopus, Web of Science, and ScienceDirect. The search was based on the keywords: SIBO, small intestinal bacterial overgrowth syndrome, dysbiosis, diagnosis of SIBO, and treatments of SIBO. Articles published between 2011 and 2024 were included, with at least 80% of the sources published after 2015 to ensure up-to-date information.
Basic Results
SIBO is associated with diverse etiological factors, including gastrointestinal motility disorders, anatomical abnormalities, and immune deficiencies. Diagnosis primarily relies on clinical history and breath tests, though these have limitations in accuracy. Antimicrobial therapy, alongside management of nutritional deficiencies and the underlying condition, are the cornerstone of treatment.
Conclusions
SIBO presents with nonspecific symptoms commonly seen in clinical practice, especially in elderly and high-risk patients. Early diagnosis and appropriate treatment can significantly improve patients' quality of life.
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| format | Article |
| id | doaj-art-4fe4914e2069449fbc230afde3090ef9 |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-4fe4914e2069449fbc230afde3090ef92024-12-25T08:21:55ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182024-12-013610.12775/QS.2024.36.56729Small Intestinal Bacterial Overgrowth Syndrome: New Clinical Insights for Multimorbid and High-Risk PatientsKrzysztof Nowakowski0https://orcid.org/0009-0006-6136-0730Zuzanna Mularczyk1https://orcid.org/0009-0000-6788-2739Magdalena Reclik2https://orcid.org/0009-0005-5359-2622Piotr Oleksy3https://orcid.org/0009-0008-0567-0317Maciej Tenderenda4https://orcid.org/0009-0007-8342-3998Collegium Medicum of University of Warmia and Mazury in OlsztynMedical University of Silesia in Katowice, Faculty of Medical Sciences in KatowiceMedical University of Silesia in Katowice, Faculty of Medical Sciences in KatowiceMedical University of Silesia in Katowice, Faculty of Medical Sciences in KatowiceMedical University of Silesia in Katowice, Faculty of Medical Sciences in Katowice Introduction Small Intestinal Bacterial Overgrowth (SIBO) syndrome has emerged as a significant clinical issue associated with various gastrointestinal and systemic conditions. The syndrome is characterized by an excessive proliferation of bacteria in the small intestine, leading to symptoms such as bloating, diarrhoea, constipation, abdominal pain, and malabsorption. These symptoms contribute to a decline in patients' quality of life, malnutrition, and nutritional deficiencies. Despite its clinical relevance, SIBO remains underdiagnosed in routine practice. Purpose of Research This study aims to review the current understanding of the pathophysiology, clinical presentation, diagnostic approaches, and treatment options for SIBO, with a focus on improving clinical recognition and management. Materials and Methods A comprehensive literature review was conducted, analyzing 31 articles sourced from PubMed, Scopus, Web of Science, and ScienceDirect. The search was based on the keywords: SIBO, small intestinal bacterial overgrowth syndrome, dysbiosis, diagnosis of SIBO, and treatments of SIBO. Articles published between 2011 and 2024 were included, with at least 80% of the sources published after 2015 to ensure up-to-date information. Basic Results SIBO is associated with diverse etiological factors, including gastrointestinal motility disorders, anatomical abnormalities, and immune deficiencies. Diagnosis primarily relies on clinical history and breath tests, though these have limitations in accuracy. Antimicrobial therapy, alongside management of nutritional deficiencies and the underlying condition, are the cornerstone of treatment. Conclusions SIBO presents with nonspecific symptoms commonly seen in clinical practice, especially in elderly and high-risk patients. Early diagnosis and appropriate treatment can significantly improve patients' quality of life. https://apcz.umk.pl/QS/article/view/56729SIBOdysbiosisDiagnosis of SIBOTreatments of SIBOSmall Intestinal Bacterial Overgrowth syndrome |
| spellingShingle | Krzysztof Nowakowski Zuzanna Mularczyk Magdalena Reclik Piotr Oleksy Maciej Tenderenda Small Intestinal Bacterial Overgrowth Syndrome: New Clinical Insights for Multimorbid and High-Risk Patients Quality in Sport SIBO dysbiosis Diagnosis of SIBO Treatments of SIBO Small Intestinal Bacterial Overgrowth syndrome |
| title | Small Intestinal Bacterial Overgrowth Syndrome: New Clinical Insights for Multimorbid and High-Risk Patients |
| title_full | Small Intestinal Bacterial Overgrowth Syndrome: New Clinical Insights for Multimorbid and High-Risk Patients |
| title_fullStr | Small Intestinal Bacterial Overgrowth Syndrome: New Clinical Insights for Multimorbid and High-Risk Patients |
| title_full_unstemmed | Small Intestinal Bacterial Overgrowth Syndrome: New Clinical Insights for Multimorbid and High-Risk Patients |
| title_short | Small Intestinal Bacterial Overgrowth Syndrome: New Clinical Insights for Multimorbid and High-Risk Patients |
| title_sort | small intestinal bacterial overgrowth syndrome new clinical insights for multimorbid and high risk patients |
| topic | SIBO dysbiosis Diagnosis of SIBO Treatments of SIBO Small Intestinal Bacterial Overgrowth syndrome |
| url | https://apcz.umk.pl/QS/article/view/56729 |
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