Tube current reduction and iterative image reconstruction for computed tomography myelography
Abstract This study aimed to systematically evaluate the impact of a low-dose (LD) protocol using tube current reduction on image quality, the confidence for intervention planning and guidance, and diagnostic yield for computed tomography (CT) myelography. We retrospectively analyzed 68 patients who...
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Nature Portfolio
2024-11-01
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| Online Access: | https://doi.org/10.1038/s41598-024-79374-3 |
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| author | Karolin J. Paprottka Vivian Schultz Karina Kupfer Meinrad Beer Claus Zimmer Jan S. Kirschke Thomas Baum Nico Sollmann |
| author_facet | Karolin J. Paprottka Vivian Schultz Karina Kupfer Meinrad Beer Claus Zimmer Jan S. Kirschke Thomas Baum Nico Sollmann |
| author_sort | Karolin J. Paprottka |
| collection | DOAJ |
| description | Abstract This study aimed to systematically evaluate the impact of a low-dose (LD) protocol using tube current reduction on image quality, the confidence for intervention planning and guidance, and diagnostic yield for computed tomography (CT) myelography. We retrospectively analyzed 68 patients who underwent CT myelography, with 34 investigations performed with a standard-dose (SD) and 34 investigations performed with a LD protocol (using tube current reduction). The different scans were matched considering variables such as sex, age, presence of spinal instrumentation, and body diameter. All images were evaluated by two readers (R1 and R2) using Likert scales. Image noise was measured using attenuation values of paraspinal muscle tissue. Images were reconstructed with model-based iterative reconstruction (post-myelography diagnostic scans) or hybrid reconstruction (planning, periprocedural, and diagnostic scans). Image quality, overall artifacts, image contrast, and confidence for planning or intervention guidance were rated good to perfect for both SD and LD scans according to evaluations of both readers. Inter-reader agreement was good to very good for the images from intervention planning (κ ≥ 0.80) as well as for intervention guidance (κ ≥ 0.77), as well as for diagnostic scans (κ ≥ 0.85). Image noise was similar between SD and LD scans performed for planning of the interventional procedures (model-based iterative reconstruction: SD 45.37 ± 7.29 HU vs. LD 45.17 ± 9.12 HU; hybrid reconstruction: SD 46.05 ± 7.43 HU vs. LD 45.05 ± 8.69 HU; p > 0.05). The volume-weighted CT dose index (CTDIvol) and size-specific dose estimate (SSDE) were significantly lower for the planning scans as well as the periprocedural scans when using the LD protocol as compared to the SD protocol (p < 0.05). In conclusion, implementation of a LD protocol with tube current reduction for CT myelography is a feasible option to reduce radiation exposure, especially when combined with iterative image reconstruction. In our study, LD imaging did not have a relevant negative impact on image quality, confidence for intervention planning or guidance, or diagnostic certainty for CT myelography. |
| format | Article |
| id | doaj-art-4f4865658e1e43c5b1ea064beb50ed16 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-4f4865658e1e43c5b1ea064beb50ed162024-11-17T12:20:48ZengNature PortfolioScientific Reports2045-23222024-11-0114111310.1038/s41598-024-79374-3Tube current reduction and iterative image reconstruction for computed tomography myelographyKarolin J. Paprottka0Vivian Schultz1Karina Kupfer2Meinrad Beer3Claus Zimmer4Jan S. Kirschke5Thomas Baum6Nico Sollmann7Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of MunichDepartment of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of MunichDepartment of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of MunichDepartment of Diagnostic and Interventional Radiology, University Hospital UlmDepartment of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of MunichDepartment of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of MunichDepartment of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of MunichDepartment of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of MunichAbstract This study aimed to systematically evaluate the impact of a low-dose (LD) protocol using tube current reduction on image quality, the confidence for intervention planning and guidance, and diagnostic yield for computed tomography (CT) myelography. We retrospectively analyzed 68 patients who underwent CT myelography, with 34 investigations performed with a standard-dose (SD) and 34 investigations performed with a LD protocol (using tube current reduction). The different scans were matched considering variables such as sex, age, presence of spinal instrumentation, and body diameter. All images were evaluated by two readers (R1 and R2) using Likert scales. Image noise was measured using attenuation values of paraspinal muscle tissue. Images were reconstructed with model-based iterative reconstruction (post-myelography diagnostic scans) or hybrid reconstruction (planning, periprocedural, and diagnostic scans). Image quality, overall artifacts, image contrast, and confidence for planning or intervention guidance were rated good to perfect for both SD and LD scans according to evaluations of both readers. Inter-reader agreement was good to very good for the images from intervention planning (κ ≥ 0.80) as well as for intervention guidance (κ ≥ 0.77), as well as for diagnostic scans (κ ≥ 0.85). Image noise was similar between SD and LD scans performed for planning of the interventional procedures (model-based iterative reconstruction: SD 45.37 ± 7.29 HU vs. LD 45.17 ± 9.12 HU; hybrid reconstruction: SD 46.05 ± 7.43 HU vs. LD 45.05 ± 8.69 HU; p > 0.05). The volume-weighted CT dose index (CTDIvol) and size-specific dose estimate (SSDE) were significantly lower for the planning scans as well as the periprocedural scans when using the LD protocol as compared to the SD protocol (p < 0.05). In conclusion, implementation of a LD protocol with tube current reduction for CT myelography is a feasible option to reduce radiation exposure, especially when combined with iterative image reconstruction. In our study, LD imaging did not have a relevant negative impact on image quality, confidence for intervention planning or guidance, or diagnostic certainty for CT myelography.https://doi.org/10.1038/s41598-024-79374-3Dose reductionMulti-detector computed tomographyMyelographyImage qualityRadiation exposure |
| spellingShingle | Karolin J. Paprottka Vivian Schultz Karina Kupfer Meinrad Beer Claus Zimmer Jan S. Kirschke Thomas Baum Nico Sollmann Tube current reduction and iterative image reconstruction for computed tomography myelography Scientific Reports Dose reduction Multi-detector computed tomography Myelography Image quality Radiation exposure |
| title | Tube current reduction and iterative image reconstruction for computed tomography myelography |
| title_full | Tube current reduction and iterative image reconstruction for computed tomography myelography |
| title_fullStr | Tube current reduction and iterative image reconstruction for computed tomography myelography |
| title_full_unstemmed | Tube current reduction and iterative image reconstruction for computed tomography myelography |
| title_short | Tube current reduction and iterative image reconstruction for computed tomography myelography |
| title_sort | tube current reduction and iterative image reconstruction for computed tomography myelography |
| topic | Dose reduction Multi-detector computed tomography Myelography Image quality Radiation exposure |
| url | https://doi.org/10.1038/s41598-024-79374-3 |
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