Cohort profile: the ChicagO Multiethnic Prevention and Surveillance Study (COMPASS)

Purpose The ChicagO Multiethnic Prevention and Surveillance Study or ‘COMPASS’ is a population-based cohort study with a goal to examine the risk and determinants of cancer and chronic disease. COMPASS aims to address factors causing and/or exacerbating health disparities using a precision health ap...

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Main Authors: Habibul Ahsan, Farzana Jasmine, Muhammad G Kibriya, Briseis Aschebrook-Kilfoy, Liz Stepniak, Rajan Gopalakrishnan, Andrew Craver, Paul Zakin, Saira Tasmin, Karen E Kim, Kathleen H Goss, Marcy List, Michelle LeBeau
Format: Article
Language:English
Published: BMJ Publishing Group 2020-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/9/e038481.full
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author Habibul Ahsan
Farzana Jasmine
Muhammad G Kibriya
Briseis Aschebrook-Kilfoy
Liz Stepniak
Rajan Gopalakrishnan
Andrew Craver
Paul Zakin
Saira Tasmin
Karen E Kim
Kathleen H Goss
Marcy List
Michelle LeBeau
author_facet Habibul Ahsan
Farzana Jasmine
Muhammad G Kibriya
Briseis Aschebrook-Kilfoy
Liz Stepniak
Rajan Gopalakrishnan
Andrew Craver
Paul Zakin
Saira Tasmin
Karen E Kim
Kathleen H Goss
Marcy List
Michelle LeBeau
author_sort Habibul Ahsan
collection DOAJ
description Purpose The ChicagO Multiethnic Prevention and Surveillance Study or ‘COMPASS’ is a population-based cohort study with a goal to examine the risk and determinants of cancer and chronic disease. COMPASS aims to address factors causing and/or exacerbating health disparities using a precision health approach by recruiting diverse participants in Chicago, with an emphasis on those historically underrepresented in biomedical research.Participants Nearly 8000 participants have been recruited from 72 of the 77 Chicago community areas. Enrolment entails the completion of a 1-hour long survey, consenting for past and future medical records from all sources, the collection of clinical and physical measurement data and the on-site collection of biological samples including blood, urine and saliva. Indoor air monitoring data and stool samples are being collected from a subset of participants. On collection, all biological samples are processed and aliquoted within 24 hours before long-term storage and subsequent analysis.Findings to date The cohort reported an average age of 53.7 years, while 80.5% identified as African-American, 5.7% as Hispanic and 47.8% as men. Over 50% reported earning less than US$15 000 yearly, 35% were obese and 47.8% were current smokers. Moreover, 38% self-reported having had a diagnosis of hypertension, while 66.4% were measured as hypertensive at enrolment.Future plans We plan to expand recruitment up to 100 000 participants from the Chicago metropolitan area in the next decade using a hybrid community and clinic-based recruitment framework that incorporates data collection through mobile medical units. Follow-up data collection from current cohort members will include serial samples, as well as longitudinal health, lifestyle and behavioural assessment. We will supplement self-reported data with electronic medical records, expand the collection of biometrics and biosamples to facilitate increasing digital epidemiological study designs and link to state and/or national level databases to ascertain outcomes. The results and findings will inform potential opportunities for precision disease prevention and mitigation in Chicago and other urban areas with a diverse population.Registration NA.
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spelling doaj-art-4f454e12814c4008867e3cbc294839092025-01-08T23:25:10ZengBMJ Publishing GroupBMJ Open2044-60552020-09-0110910.1136/bmjopen-2020-038481Cohort profile: the ChicagO Multiethnic Prevention and Surveillance Study (COMPASS)Habibul Ahsan0Farzana Jasmine1Muhammad G Kibriya2Briseis Aschebrook-Kilfoy3Liz Stepniak4Rajan Gopalakrishnan5Andrew Craver6Paul Zakin7Saira Tasmin8Karen E Kim9Kathleen H Goss10Marcy List11Michelle LeBeau12Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USADepartment of Public Health Sciences, The University of Chicago, Chicago, Illinois, USADepartment of Public Health Sciences, The University of Chicago, Chicago, Illinois, USADepartment of Public Health Sciences, The University of Chicago, Chicago, Illinois, USADepartment of Public Health Sciences, The University of Chicago, Chicago, Illinois, USAComprehensive Cancer Center, University of Chicago, Chicago, Illinois, USAInstitute for Population and Precision Health, The University of Chicago, Chicago, Illinois, USAInstitute for Population and Precision Health, The University of Chicago, Chicago, Illinois, USADepartment of Public Health Sciences, The University of Chicago, Chicago, Illinois, USAComprehensive Cancer Center, University of Chicago, Chicago, Illinois, USAComprehensive Cancer Center, University of Chicago, Chicago, Illinois, USAComprehensive Cancer Center, University of Chicago, Chicago, Illinois, USAComprehensive Cancer Center, University of Chicago, Chicago, Illinois, USAPurpose The ChicagO Multiethnic Prevention and Surveillance Study or ‘COMPASS’ is a population-based cohort study with a goal to examine the risk and determinants of cancer and chronic disease. COMPASS aims to address factors causing and/or exacerbating health disparities using a precision health approach by recruiting diverse participants in Chicago, with an emphasis on those historically underrepresented in biomedical research.Participants Nearly 8000 participants have been recruited from 72 of the 77 Chicago community areas. Enrolment entails the completion of a 1-hour long survey, consenting for past and future medical records from all sources, the collection of clinical and physical measurement data and the on-site collection of biological samples including blood, urine and saliva. Indoor air monitoring data and stool samples are being collected from a subset of participants. On collection, all biological samples are processed and aliquoted within 24 hours before long-term storage and subsequent analysis.Findings to date The cohort reported an average age of 53.7 years, while 80.5% identified as African-American, 5.7% as Hispanic and 47.8% as men. Over 50% reported earning less than US$15 000 yearly, 35% were obese and 47.8% were current smokers. Moreover, 38% self-reported having had a diagnosis of hypertension, while 66.4% were measured as hypertensive at enrolment.Future plans We plan to expand recruitment up to 100 000 participants from the Chicago metropolitan area in the next decade using a hybrid community and clinic-based recruitment framework that incorporates data collection through mobile medical units. Follow-up data collection from current cohort members will include serial samples, as well as longitudinal health, lifestyle and behavioural assessment. We will supplement self-reported data with electronic medical records, expand the collection of biometrics and biosamples to facilitate increasing digital epidemiological study designs and link to state and/or national level databases to ascertain outcomes. The results and findings will inform potential opportunities for precision disease prevention and mitigation in Chicago and other urban areas with a diverse population.Registration NA.https://bmjopen.bmj.com/content/10/9/e038481.full
spellingShingle Habibul Ahsan
Farzana Jasmine
Muhammad G Kibriya
Briseis Aschebrook-Kilfoy
Liz Stepniak
Rajan Gopalakrishnan
Andrew Craver
Paul Zakin
Saira Tasmin
Karen E Kim
Kathleen H Goss
Marcy List
Michelle LeBeau
Cohort profile: the ChicagO Multiethnic Prevention and Surveillance Study (COMPASS)
BMJ Open
title Cohort profile: the ChicagO Multiethnic Prevention and Surveillance Study (COMPASS)
title_full Cohort profile: the ChicagO Multiethnic Prevention and Surveillance Study (COMPASS)
title_fullStr Cohort profile: the ChicagO Multiethnic Prevention and Surveillance Study (COMPASS)
title_full_unstemmed Cohort profile: the ChicagO Multiethnic Prevention and Surveillance Study (COMPASS)
title_short Cohort profile: the ChicagO Multiethnic Prevention and Surveillance Study (COMPASS)
title_sort cohort profile the chicago multiethnic prevention and surveillance study compass
url https://bmjopen.bmj.com/content/10/9/e038481.full
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