Integrating network toxicology, transcriptomics, and metabolomics uncovers the hepatotoxic mechanisms of okadaic acid in LO2 cells
Okadaic acid (OKA), a potent phycotoxin existed in shellfish, is known to cause liver damage. However, the hepatic mechanisms underlying its toxicity remain poorly understood. In this work, we aim to elucidate the hepatotoxic mechanisms of OKA by integrating network toxicology with transcriptomic an...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325009212 |
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