Safety, tolerability, and efficacy of an in‐class combination therapy switch from bosentan plus sildenafil to ambrisentan plus tadalafil in children with pulmonary arterial hypertension

Safety, tolerability, and efficacy of an in‐class combination therapy switch from bosentan plus sildenafil to ambrisentan plus tadalafil in children with pulmonary arterial hypertension

Abstract The aim of this single‐centre retrospective observational study was to evaluate the safety, tolerability, and efficacy of an in‐class combination therapy switch from bosentan plus sildenafil to ambrisentan plus tadalafil in children with pulmonary arterial hypertension. Children aged over 5...

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Main Authors: Cara Morgan, Nikmah Idris, Kathy Elterefi, Luca Di Ienno, Andrew Constantine, Sadia Quyam, Roberta Bini, Shahin Moledina
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Pulmonary Circulation
Subjects:
pulmonary artery hypertension
pulmonary hypertension
rare pediatric lung disease
treatment
Online Access:https://doi.org/10.1002/pul2.70011
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