Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells

Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells

<b>Background/Objectives</b>: Macrophages play a pivotal role in various pathogenic processes, necessitating the development of efficient differentiation techniques to meet the high demand for these cells in research and therapy. Human macrophages can be obtained via culturing peripheral...

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Bibliographic Details
Main Authors: Qimin Hai, Peter Bazeley, Juying Han, Gregory Brubaker, Jennifer Powers, Claudia M. Diaz-Montero, Jonathan D. Smith
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomedicines
Subjects:
iPSC
macrophage
cell differentiation
embryoid body
polarization
M1-like macrophage
Online Access:https://www.mdpi.com/2227-9059/13/1/99
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