HSF1 at the crossroads of chemoresistance: from current insights to future horizons in cell death mechanisms
Heat Shock Factor 1 (HSF1) is a major transcriptional factor regulating the heat shock response and has become a potential target for overcoming cancer chemoresistance. This review comprehensively examines HSF1’s role in chemoresistance and its potential as a therapeutic target in cancer. We explore...
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Main Authors: | Shruti Ghai, Rejina Shrestha, Kuo-Hui Su |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-01-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2024.1500880/full |
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