Conessine alleviates PTZ-induced epilepsy in rat model via attenuating neuroinflammation and oxidative stress

Conessine alleviates PTZ-induced epilepsy in rat model via attenuating neuroinflammation and oxidative stress

Epilepsy is a complex neurological disorder which affects the quality life of individual and also hinders the economic status of both the individuals and the country since it requires prolonged medications. The etiology of epilepsy is varied and the neuroinflammation has been considered to be the pr...

Full description

Saved in:

Bibliographic Details
Main Authors:	Fang Chen, Tingting Peng, Mengjiao Gou
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Series:	Arabian Journal of Chemistry
Subjects:	Epilepsy Seizures Neuroinflammation Oxidative stress Conessine
Online Access:	http://www.sciencedirect.com/science/article/pii/S1878535224004118
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Chrysophanol attenuates cognitive impairment, neuroinflammation, and oxidative stress by TLR4/NFκB-Nrf2/HO-1 and BDNF/VEGF signaling in stress-intensified PTZ induced epilepsy in mice
by: Jehan Zeb Khan, et al.
Published: (2024-11-01)

Ivermectin as a promising therapeutic option for onchocerciasis‐associated epilepsy
by: Mohammad Amin Manavi, et al.
Published: (2025-02-01)

Pirfenidone regulates seizures through the HMGB1/TLR4 axis to improve cognitive functions and modulate oxidative stress and neurotransmitters in PTZ-induced kindling in mice
by: Mansi Dahalia, et al.
Published: (2025-01-01)

The implications of frailty in older adults with epilepsy
by: Syeda Amrah Hashmi, et al.
Published: (2024-12-01)

Anti-Epileptic Activity of Mitocurcumin in a Zebrafish–Pentylenetetrazole (PTZ) Epilepsy Model
by: Alin Dumitru Ciubotaru, et al.
Published: (2024-11-01)

Mortality in older adults with epilepsy: An understudied entity
by: Syeda Amrah Hashmi, et al.
Published: (2025-02-01)

Sex Differences in Epilepsies: A Narrative Review
by: Ali A. Asadi-Pooya, et al.
Published: (2024-12-01)

Management and outcomes among older adults with generalized epilepsy in routine clinical practice
by: MarieElena Byrnes, et al.
Published: (2025-02-01)

Influence of sleep on seizures and interictal epileptiform discharges in epilepsy
by: Jun-Sang Sunwoo
Published: (2025-01-01)

Incidence and Predictors of Later Epilepsy in Neonates with Encephalopathy: The Impact of Electrographic Seizures
by: Carol M. Stephens, et al.
Published: (2025-02-01)

Therapeutic efficacy of voltage-gated sodium channel inhibitors in epilepsy
by: John Agbo, et al.
Published: (2023-06-01)

Self-reported exercise engagement and seizure control – A preliminary survey of people with epilepsy at a safety-net hospital
by: Ariel Farb, et al.
Published: (2024-01-01)

Neuropsychological morbidity in the First Seizure Clinic: Prominent mood symptoms and memory issues in epilepsy
by: Remy Pugh, et al.
Published: (2025-02-01)

Decanoic acid-enriched ketogenic diet in refractory epilepsy
by: Hui Jin Shin, et al.
Published: (2025-01-01)

Stroke-related epilepsy in the rehabilitation setting: Insights from the inpatient post-stroke rehabilitation study – RIPS
by: Maenia Scarpino, et al.
Published: (2024-01-01)

To be or not to be: The dilemma over the prognostic role of epilepsy at presentation in patients with glioblastoma – a systematic review and meta-analysis
by: Jessica Rossi, et al.
Published: (2024-12-01)

Emotional comorbidities in epilepsy result from seizure-induced corticosterone activity
by: Renaud C. Gom, et al.
Published: (2024-11-01)

Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice
by: Chu X, et al.
Published: (2025-01-01)

Clinician Understanding, Acceptance and utilization of Ketogenic diet therapy for epilepsy in Australia and New Zealand: An online survey
by: Tania E. Farrar, et al.
Published: (2024-01-01)

Medial pulvinar stimulation for focal drug-resistant epilepsy: interim 12-month results of the PULSE study
by: Francesca Pizzo, et al.
Published: (2024-12-01)

Development and internal validation of a prognostic model for predicting tonic-clonic seizures during pregnancy in women with epilepsy
by: Yanru Du, et al.
Published: (2024-12-01)

Impact of COVID-19 vaccination in patients with epilepsy
by: Haidy Elshebawy, et al.
Published: (2024-12-01)

Enhancing Epilepsy Seizure Detection Through Advanced EEG Preprocessing Techniques and Peak-to-Peak Amplitude Fluctuation Analysis
by: Muawiyah A. Bahhah, et al.
Published: (2024-11-01)

Interplay of epilepsy and long-term potentiation: implications for memory
by: Luis A. Marin-Castañeda, et al.
Published: (2025-01-01)

“Never Judge a Book by its Cover”-The socio-cultural aspects of non-epileptic seizures in India-A case study
by: Sudip Bhattacharya, et al.
Published: (2023-02-01)

Irisin Attenuates Neuroinflammation Targeting the NLRP3 Inflammasome
by: Francesca Martina Filannino, et al.
Published: (2024-11-01)

Epilepsy in Loeys-Dietz Syndrome: The Rare Concurrence of a Connective Tissue and Neuronal Migration Disorder
by: Fatima Farid Mir, et al.
Published: (2024-10-01)

One‐year seizure freedom and quality of life in patients with drug‐resistant epilepsy receiving adjunctive vagus nerve stimulation in Japan
by: Naoki Tani, et al.
Published: (2024-12-01)

Glycyrrhizin as a potential disease-modifying therapy for epilepsy: insights into targeting pyroptosis to exert neuroprotective and anticonvulsant effects
by: Lei Wei, et al.
Published: (2025-01-01)

A Prospective Single-Arm Cohort Study of Immune-mediated Seizures/Epilepsy Without Encephalopathy (ISEWE) in Children from a Tertiary Care Hospital in South India
by: Basavanagowda Thanuja, et al.
Published: (2024-12-01)

Effect of Pergularia daemia Forsk. aqueous extract in Pentylenetetrazole-induced wistar albino rats Antiseizure study
by: Agnel Arul John Nayagam, et al.
Published: (2024-12-01)

Geraniol Ameliorates Pentylenetetrazol-Induced Epilepsy, Neuroinflammation, and Oxidative Stress via Modulating the GABAergic Tract: In vitro and in vivo studies
by: Younis NS, et al.
Published: (2024-12-01)

Diagnostic efficiency of exome-based sequencing in pediatric patients with epilepsy
by: Huafang Zou, et al.
Published: (2025-01-01)

Novel nonsense mutation in gene CHRNA2 identified by whole-genome sequencing in infant with epilepsy disorder: A case report
by: Sultan Makhmetov, et al.
Published: (2025-01-01)

Cerebrospinal fluid‐specific oligoclonal bands in dogs with idiopathic epilepsy
by: Junwei Föhr, et al.
Published: (2025-01-01)

A multicultural comparative study of self‐stigma in epilepsy: Differences across four cultures
by: Takayuki Iwayama, et al.
Published: (2024-12-01)

Evaluation of School Absenteeism and Affecting Factors in Child Patients with Epilepsy
by: Ayşegül Danış, et al.
Published: (2022-08-01)

The asymptomatic bacteriuria in the patients with epilepsy: A cross-sectional study
by: Yu-Shiue Chen, et al.
Published: (2024-12-01)

A novel hydrogen sulfide donor reduces neuroinflammation and seizures by activating ATP-sensitive potassium channels
by: Qiyun Kang, et al.
Published: (2024-02-01)

Equine-assisted therapy in quality of life and functioning of people with active epilepsy: A feasibility study
by: Franciely Oliveira de Andrade Santos, et al.
Published: (2024-01-01)