Conjoint analysis of methylation, transcriptomic, and proteomic profiles in pemphigus vulgaris

Conjoint analysis of methylation, transcriptomic, and proteomic profiles in pemphigus vulgaris

Abstract Background The underlying pathogenesis of pemphigus vulgaris, an autoimmune skin disorder, remains incompletely understood. An integrative analysis comprising DNA methylation, mRNA expression, and proteomic data in patients with pemphigus vulgaris was conducted to identify potential pathoge...

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Bibliographic Details
Main Authors: Xiaojia Luo, Jianting Ouyang, Fuqiong Jiang, Yaozhong Zhang, Yuan Wang, Yongzhuo Wu, Lingyu Hu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Expression profile
Methylation
Pathogenesis
Pemphigus
Platelet activation
Proteomics
Online Access:https://doi.org/10.1186/s13023-024-03458-6
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