A novel neutralizing monoclonal antibody recognizes a linear antigenic epitope of the spike protein of swine acute diarrhoea syndrome coronavirus

A novel neutralizing monoclonal antibody recognizes a linear antigenic epitope of the spike protein of swine acute diarrhoea syndrome coronavirus

Abstract Swine acute diarrhoea syndrome coronavirus (SADS-CoV) causes vomiting, severe diarrhoea and death in newborn piglets. The spike (S) protein plays a crucial role in promoting virus invasion and inducing neutralizing antibody production. In this study, the extracellular region of the S protei...

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Bibliographic Details
Main Authors: Lin Zhang, Hui-Zhen Liu, Yuexiao Lian, Yujun Zhu, Miaoli Wu, Jianbo Liu, Feng Cong
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Virology Journal
Subjects:
Swine acute diarrhoea syndrome coronavirus (SADS-CoV)
Neutralizing antibodies
Antigenic epitope
Online Access:https://doi.org/10.1186/s12985-024-02562-0
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