Tetramethylpyrazine and paeoniflorin combination (TMP-PF) alleviates atherosclerosis progress by reducing hyperlipemia and inhibiting plaque angiogenesis via the NR4A1/VEGFR2 pathway

Tetramethylpyrazine and paeoniflorin combination (TMP-PF) alleviates atherosclerosis progress by reducing hyperlipemia and inhibiting plaque angiogenesis via the NR4A1/VEGFR2 pathway

Atherosclerosis remains a great threat to human health worldwide. Previous studies found that tetramethylpyrazine (TMP) and paeonif lorin (PF) combination (TMP-PF) exerts anti-atherosclerotic effects in vitro. However, whether TMP-PF improves atherosclerosis in vivo needs further exploration. The pr...

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Bibliographic Details
Main Authors: Rong Yuan, Qiqi Xin, Weili Shi, Yu Miao, Zhengchuan Zhu, Yahui Yuan, Ying Chen, Xiaoning Chen, Sean Xiao Leng, Keji Chen, Weihong Cong
Format: Article
Language:English
Published: Tsinghua University Press 2024-09-01
Series:Food Science and Human Wellness
Subjects:
atherosclerosis
hyperlipemia
angiogenesis
plaque stability
chinese medicine
tetramethylpyrazine
paeoniflorin
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2022.9250212
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