N-Aryl Benzimidazole and Benzotriazole Derivatives and Their Hybrids as Cytotoxic Agents: Design, Synthesis and Structure–Activity Relationship Studies

N-Aryl Benzimidazole and Benzotriazole Derivatives and Their Hybrids as Cytotoxic Agents: Design, Synthesis and Structure–Activity Relationship Studies

The era of chemotherapy began in the 1940s, which is the basis of traditional antitumor approaches and, being one of the most high-tech treatment methods, is still widely used to treat various types of cancer. A promising direction in modern medicinal chemistry is currently the creation of hybrid mo...

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Bibliographic Details
Main Authors: Yulia R. Aleksandrova, Natalia S. Nikolaeva, Inna A. Shagina, Karina D. Smirnova, Alla A. Zubishina, Alexander I. Khlopotinin, Artem N. Fakhrutdinov, Alexander L. Khokhlov, Roman S. Begunov, Margarita E. Neganova
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
hybrid molecules
heterocycles
benzimidazoles
benzotriazoles
diphenylamines
anticancer agents
Online Access:https://www.mdpi.com/1420-3049/29/22/5360
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