Methylome analysis in long-lived men deciphers DNA methylation modifications associated with male longevity in humans
Summary: Men, despite having a lower likelihood of longevity compared to women, generally exhibit better health status when they achieve longevity. The role of DNA methylation in this paradox remains unclear. We performed whole-genome bisulfite sequencing on long-lived men (LLMs), long-lived women (...
Saved in:
Main Authors: | Fu-Hui Xiao, Hao-Tian Wang, Long Zhao, Tian-Rui Xia, Li-Qin Yang, Si-Yu Ma, Qing-Peng Kong |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
|
Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124724015092 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy
by: Mari Aikio, et al.
Published: (2025-01-01) -
Phosphorylation of SIRT7 by ATM causes DNA mismatch repair downregulation and adaptive mutability during chemotherapy
by: Lianhui Sun, et al.
Published: (2025-02-01) -
Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs
by: Kejia Zhang, et al.
Published: (2025-01-01) -
KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition
by: Deniz Gökbuget, et al.
Published: (2025-02-01) -
G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration
by: Liana C. Boraas, et al.
Published: (2025-02-01)