Metallaphotocatalytic triple couplings for modular synthesis of elaborate N-trifluoroalkyl anilines

Abstract The integration of trifluoromethyl groups and three-dimensional quaternary carbon moieties into organic molecules has emerged as a prominent strategy in medicinal chemistry to augment drug efficacy. Although trifluoromethyl (hetero)aromatic amines and derivatives are prevalent frameworks in...

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Bibliographic Details
Main Authors: Ting Zhou, Zhong-Wei Zhang, Jing Nie, Fuk Yee Kwong, Jun-An Ma, Chi Wai Cheung
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53828-8
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