Metallaphotocatalytic triple couplings for modular synthesis of elaborate N-trifluoroalkyl anilines
Abstract The integration of trifluoromethyl groups and three-dimensional quaternary carbon moieties into organic molecules has emerged as a prominent strategy in medicinal chemistry to augment drug efficacy. Although trifluoromethyl (hetero)aromatic amines and derivatives are prevalent frameworks in...
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| Main Authors: | Ting Zhou, Zhong-Wei Zhang, Jing Nie, Fuk Yee Kwong, Jun-An Ma, Chi Wai Cheung |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-53828-8 |
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