Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis
Abstract The precise measurement of cell temperature and an in‐depth understanding of thermogenic processes are critical in unraveling the complexities of cellular metabolism and its implications for health and disease. This review focuses on the mechanisms of local temperature generation within cel...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Advanced Science |
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| Online Access: | https://doi.org/10.1002/advs.202402135 |
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| author | Hanliang Zhu Haotian Xu Yue Zhang Jan Brodský Imrich Gablech Marie Korabečná Pavel Neuzil |
| author_facet | Hanliang Zhu Haotian Xu Yue Zhang Jan Brodský Imrich Gablech Marie Korabečná Pavel Neuzil |
| author_sort | Hanliang Zhu |
| collection | DOAJ |
| description | Abstract The precise measurement of cell temperature and an in‐depth understanding of thermogenic processes are critical in unraveling the complexities of cellular metabolism and its implications for health and disease. This review focuses on the mechanisms of local temperature generation within cells and the array of methods developed for accurate temperature assessment. The contact and noncontact techniques are introduced, including infrared thermography, fluorescence thermometry, and other innovative approaches to localized temperature measurement. The role of thermogenesis in cellular metabolism, highlighting the integral function of temperature regulation in cellular processes, environmental adaptation, and the implications of thermogenic dysregulation in diseases such as metabolic disorders and cancer are further discussed. The challenges and limitations in this field are critically analyzed while technological advancements and future directions are proposed to overcome these barriers. This review aims to provide a consolidated resource for current methodologies, stimulate discussion on the limitations and challenges, and inspire future innovations in the study of cellular thermodynamics. |
| format | Article |
| id | doaj-art-4dada15a9437442db7ad41b600fe5f19 |
| institution | Kabale University |
| issn | 2198-3844 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj-art-4dada15a9437442db7ad41b600fe5f192025-01-09T11:44:45ZengWileyAdvanced Science2198-38442025-01-01121n/an/a10.1002/advs.202402135Exploring the Frontiers of Cell Temperature Measurement and ThermogenesisHanliang Zhu0Haotian Xu1Yue Zhang2Jan Brodský3Imrich Gablech4Marie Korabečná5Pavel Neuzil6School of Mechanical Engineering Northwestern Polytechnical University Xi'an Shaanxi 710072 P. R. ChinaSchool of Mechanical Engineering Northwestern Polytechnical University Xi'an Shaanxi 710072 P. R. ChinaSchool of Mechanical Engineering Northwestern Polytechnical University Xi'an Shaanxi 710072 P. R. ChinaDepartment of Microelectronics The Faculty of Electrical Engineering and Communication Technology Brno University of Technology Technická 3058/10 Brno 616 00 Czech RepublicDepartment of Microelectronics The Faculty of Electrical Engineering and Communication Technology Brno University of Technology Technická 3058/10 Brno 616 00 Czech RepublicInstitute of Biology and Medical Genetics, First Faculty of Medicine Charles University and General University Hospital in Prague Albertov 4 Prague 128 00 Czech RepublicSchool of Mechanical Engineering Northwestern Polytechnical University Xi'an Shaanxi 710072 P. R. ChinaAbstract The precise measurement of cell temperature and an in‐depth understanding of thermogenic processes are critical in unraveling the complexities of cellular metabolism and its implications for health and disease. This review focuses on the mechanisms of local temperature generation within cells and the array of methods developed for accurate temperature assessment. The contact and noncontact techniques are introduced, including infrared thermography, fluorescence thermometry, and other innovative approaches to localized temperature measurement. The role of thermogenesis in cellular metabolism, highlighting the integral function of temperature regulation in cellular processes, environmental adaptation, and the implications of thermogenic dysregulation in diseases such as metabolic disorders and cancer are further discussed. The challenges and limitations in this field are critically analyzed while technological advancements and future directions are proposed to overcome these barriers. This review aims to provide a consolidated resource for current methodologies, stimulate discussion on the limitations and challenges, and inspire future innovations in the study of cellular thermodynamics.https://doi.org/10.1002/advs.202402135cell temperature measurementintracellular thermogenesiscellular thermodynamicsmetabolic disorderscancer thermotherapy |
| spellingShingle | Hanliang Zhu Haotian Xu Yue Zhang Jan Brodský Imrich Gablech Marie Korabečná Pavel Neuzil Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis Advanced Science cell temperature measurement intracellular thermogenesis cellular thermodynamics metabolic disorders cancer thermotherapy |
| title | Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis |
| title_full | Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis |
| title_fullStr | Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis |
| title_full_unstemmed | Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis |
| title_short | Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis |
| title_sort | exploring the frontiers of cell temperature measurement and thermogenesis |
| topic | cell temperature measurement intracellular thermogenesis cellular thermodynamics metabolic disorders cancer thermotherapy |
| url | https://doi.org/10.1002/advs.202402135 |
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