Significance of Initial Chest CT Severity Score (CTSS) and Patient Characteristics in Predicting Outcomes in Hospitalized COVID-19 Patients: A Single Center Study
The aim of this study is to examine the prognostic role of initial chest computed tomography severity score index (CTSS) and its association with demographic, socio-epidemiological, and clinical parameters in COVID-19 hospitalized patients. A retrospective study included patients who were hospitaliz...
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2024-10-01
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| author | Aleksandra Milenkovic Simon Nikolic Zlatan Elek Jelena Aritonovic Pribakovic Aleksandra Ilic Kristina Bulatovic Milos Gasic Bojan Jaksic Milan Stojanovic Dusica Miljkovic Jaksic Arijeta Kostic Roksanda Krivcevic Nikolcevic Aleksandra Balovic Filip Petrović |
| author_facet | Aleksandra Milenkovic Simon Nikolic Zlatan Elek Jelena Aritonovic Pribakovic Aleksandra Ilic Kristina Bulatovic Milos Gasic Bojan Jaksic Milan Stojanovic Dusica Miljkovic Jaksic Arijeta Kostic Roksanda Krivcevic Nikolcevic Aleksandra Balovic Filip Petrović |
| author_sort | Aleksandra Milenkovic |
| collection | DOAJ |
| description | The aim of this study is to examine the prognostic role of initial chest computed tomography severity score index (CTSS) and its association with demographic, socio-epidemiological, and clinical parameters in COVID-19 hospitalized patients. A retrospective study included patients who were hospitalized in the COVID Hospital of the Clinical Hospital Center Kosovska Mitrovica from July 2020 to March 2022. We compared patient characteristics and outcome of their hospital stay with values of CT severity score (mild, moderate, and severe form of the disease). Patients with severe disease were statistically significantly older, they treated more days, and they presented statistically significant highest mortality rate compared to mild and moderate forms. Smokers and obese were significantly more frequent among patients with higher CT, while vaccinated patients were more common among those with a mild form. Biochemical parameters at admission also showed statistical significance between the examined groups. We can conclude that by employing the initial CT severity score as the strongest predictor of mortality, it is possible to predict the outcome in hospitalized patients. A comprehensive examination of the patient upon admission, including determining the extent of inflammatory changes in the lungs using computed tomography, the levels of oxygen saturation, and other laboratory parameters, can assist doctors in making an adequate clinical evaluation and apply appropriate therapeutic protocols in the treatment of COVID-19. |
| format | Article |
| id | doaj-art-4d2b45c6e8424392b82217cabdbdd406 |
| institution | Kabale University |
| issn | 1999-4915 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj-art-4d2b45c6e8424392b82217cabdbdd4062024-11-26T18:25:16ZengMDPI AGViruses1999-49152024-10-011611168310.3390/v16111683Significance of Initial Chest CT Severity Score (CTSS) and Patient Characteristics in Predicting Outcomes in Hospitalized COVID-19 Patients: A Single Center StudyAleksandra Milenkovic0Simon Nikolic1Zlatan Elek2Jelena Aritonovic Pribakovic3Aleksandra Ilic4Kristina Bulatovic5Milos Gasic6Bojan Jaksic7Milan Stojanovic8Dusica Miljkovic Jaksic9Arijeta Kostic10Roksanda Krivcevic Nikolcevic11Aleksandra Balovic12Filip Petrović13Faculty of Medicine in Priština, University of Priština Temporarily Settled in Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaFaculty of Medicine in Priština, University of Priština Temporarily Settled in Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaFaculty of Medicine in Priština, University of Priština Temporarily Settled in Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaFaculty of Medicine in Priština, University of Priština Temporarily Settled in Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaFaculty of Medicine in Priština, University of Priština Temporarily Settled in Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaFaculty of Medicine in Priština, University of Priština Temporarily Settled in Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaFaculty of Medicine in Priština, University of Priština Temporarily Settled in Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaClinical Hospital Center Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaRadiology Center, Medical Faculty, University Clinical Center Nis and University of Nis, 18000 Niš, SerbiaClinical Hospital Center Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaClinical Hospital Center Priština, 38205 Gračanica, SerbiaFaculty of Medicine in Priština, University of Priština Temporarily Settled in Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaFaculty of Medicine in Priština, University of Priština Temporarily Settled in Kosovska Mitrovica, 38220 Kosovska Mitrovica, SerbiaRadiology Center, Medical Faculty, University Clinical Center Nis and University of Nis, 18000 Niš, SerbiaThe aim of this study is to examine the prognostic role of initial chest computed tomography severity score index (CTSS) and its association with demographic, socio-epidemiological, and clinical parameters in COVID-19 hospitalized patients. A retrospective study included patients who were hospitalized in the COVID Hospital of the Clinical Hospital Center Kosovska Mitrovica from July 2020 to March 2022. We compared patient characteristics and outcome of their hospital stay with values of CT severity score (mild, moderate, and severe form of the disease). Patients with severe disease were statistically significantly older, they treated more days, and they presented statistically significant highest mortality rate compared to mild and moderate forms. Smokers and obese were significantly more frequent among patients with higher CT, while vaccinated patients were more common among those with a mild form. Biochemical parameters at admission also showed statistical significance between the examined groups. We can conclude that by employing the initial CT severity score as the strongest predictor of mortality, it is possible to predict the outcome in hospitalized patients. A comprehensive examination of the patient upon admission, including determining the extent of inflammatory changes in the lungs using computed tomography, the levels of oxygen saturation, and other laboratory parameters, can assist doctors in making an adequate clinical evaluation and apply appropriate therapeutic protocols in the treatment of COVID-19.https://www.mdpi.com/1999-4915/16/11/1683COVID-19chest CT severity scoredisease severityoutcome |
| spellingShingle | Aleksandra Milenkovic Simon Nikolic Zlatan Elek Jelena Aritonovic Pribakovic Aleksandra Ilic Kristina Bulatovic Milos Gasic Bojan Jaksic Milan Stojanovic Dusica Miljkovic Jaksic Arijeta Kostic Roksanda Krivcevic Nikolcevic Aleksandra Balovic Filip Petrović Significance of Initial Chest CT Severity Score (CTSS) and Patient Characteristics in Predicting Outcomes in Hospitalized COVID-19 Patients: A Single Center Study Viruses COVID-19 chest CT severity score disease severity outcome |
| title | Significance of Initial Chest CT Severity Score (CTSS) and Patient Characteristics in Predicting Outcomes in Hospitalized COVID-19 Patients: A Single Center Study |
| title_full | Significance of Initial Chest CT Severity Score (CTSS) and Patient Characteristics in Predicting Outcomes in Hospitalized COVID-19 Patients: A Single Center Study |
| title_fullStr | Significance of Initial Chest CT Severity Score (CTSS) and Patient Characteristics in Predicting Outcomes in Hospitalized COVID-19 Patients: A Single Center Study |
| title_full_unstemmed | Significance of Initial Chest CT Severity Score (CTSS) and Patient Characteristics in Predicting Outcomes in Hospitalized COVID-19 Patients: A Single Center Study |
| title_short | Significance of Initial Chest CT Severity Score (CTSS) and Patient Characteristics in Predicting Outcomes in Hospitalized COVID-19 Patients: A Single Center Study |
| title_sort | significance of initial chest ct severity score ctss and patient characteristics in predicting outcomes in hospitalized covid 19 patients a single center study |
| topic | COVID-19 chest CT severity score disease severity outcome |
| url | https://www.mdpi.com/1999-4915/16/11/1683 |
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