High mobility group A1 (HMGA1) promotes the tumorigenesis of colorectal cancer by increasing lipid synthesis

High mobility group A1 (HMGA1) promotes the tumorigenesis of colorectal cancer by increasing lipid synthesis

Abstract Metabolic reprogramming is a hallmark of cancer, enabling tumor cells to meet the high energy and biosynthetic demands required for their proliferation. High mobility group A1 (HMGA1) is a structural transcription factor and frequently overexpressed in human colorectal cancer (CRC). Here, w...

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Main Authors: Yuan Zhao, Meng-Jie Liu, Lei Zhang, Qi Yang, Qian-Hui Sun, Jin-Rong Guo, Xin-Yuan Lei, Kai-Yue He, Jun-Qi Li, Jing-Yu Yang, Yong-Ping Jian, Zhi-Xiang Xu
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54400-0
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