A Novel Superparamagnetic‐Responsive Hydrogel Facilitates Disc Regeneration by Orchestrating Cell Recruitment, Proliferation, and Differentiation within Hostile Inflammatory Niche

A Novel Superparamagnetic‐Responsive Hydrogel Facilitates Disc Regeneration by Orchestrating Cell Recruitment, Proliferation, and Differentiation within Hostile Inflammatory Niche

Abstract In situ disc regeneration is a meticulously orchestrated process, which involves cell recruitment, proliferation and differentiation within a local inflammatory niche. Thus far, it remains a challenge to establish a multi‐staged regulatory framework for coordinating these cellular events, t...

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Bibliographic Details
Main Authors: Borui Xue, Yan Peng, Yongfeng Zhang, Shijie Yang, Yi Zheng, Huiling Hu, Xueli Gao, Beibei Yu, Xue Gao, Shengyou Li, Haining Wu, Teng Ma, Yiming Hao, Yitao Wei, Lingli Guo, Yujie Yang, Zhenguo Wang, Tingfeng Xue, Jin Zhang, Beier Luo, Bing Xia, Jinghui Huang
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
intervertebral disc regeneration
mechanical stimulation
nucleus pulposus stem cells
superparamagnetic hydrogel
Online Access:https://doi.org/10.1002/advs.202408093
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