Structural characterization of two γδ TCR/CD3 complexes
Abstract The T-cell receptor (TCR)/CD3 complex plays an essential role in the immune response and is a key player in cancer immunotherapies. There are two classes of TCR/CD3 complexes, defined by their TCR chain usage (αβ or γδ). Recently reported structures have revealed the organization of the αβ...
Saved in:
Main Authors: | Mohammed Hoque, John Benji Grigg, Trudy Ramlall, Jennifer Jones, Luke L. McGoldrick, John C. Lin, William C. Olson, Eric Smith, Matthew C. Franklin, Tong Zhang, Kei Saotome |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-55467-5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Squamate reptiles may have compensated for the lack of γδTCR with a duplication of the TRB locus
by: Jordan M. Sampson, et al.
Published: (2025-01-01) -
TIM-3 and TIM-1 Could Regulate Decidual γδTCR Bright T Cells during Murine Pregnancy
by: Jasper Nörenberg, et al.
Published: (2019-01-01) -
γδ T-Cell Acute Lymphoblastic Leukemia/Lymphoma: Discussion of Two Pediatric Cases and Its Distinction from Other Mature γδ T-Cell Malignancies
by: Eric X. Wei, et al.
Published: (2017-01-01) -
Ex Vivo Restimulation of Human PBMC Expands a CD3+CD4-CD8-γδ+ T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination
by: B. J. Sedgmen, et al.
Published: (2013-01-01) -
Transferrin Disassociates TCR from CD3 Signaling Apparatus to Promote Metastasis
by: Ruomei Cheng, et al.
Published: (2025-01-01)