Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light
Carbonyl compounds are widely found in various chemical reactions and natural products. Herein, a light-driven carbonylative cross-coupling reaction of bromobenzene was reported. Co2(CO)8 was used as an abundant solid carbonyl source to synthesize various Michael addition products with high yields....
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Tetrahedron Green Chem |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773223124000219 |
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| _version_ | 1846137571002810368 |
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| author | Shiqian Zhang Quansheng Mou Bowen Cao Tongyu Han Mingxin Liu |
| author_facet | Shiqian Zhang Quansheng Mou Bowen Cao Tongyu Han Mingxin Liu |
| author_sort | Shiqian Zhang |
| collection | DOAJ |
| description | Carbonyl compounds are widely found in various chemical reactions and natural products. Herein, a light-driven carbonylative cross-coupling reaction of bromobenzene was reported. Co2(CO)8 was used as an abundant solid carbonyl source to synthesize various Michael addition products with high yields. This reaction has broad substrates scope with good functional group tolerance. The mechanism study indicated that the reaction is achieved by the formation of benzoyl radical from homolytic C–Co cleavage under irradiation. |
| format | Article |
| id | doaj-art-4ce56841b94e4b67a80cfb8570cb0eab |
| institution | Kabale University |
| issn | 2773-2231 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Tetrahedron Green Chem |
| spelling | doaj-art-4ce56841b94e4b67a80cfb8570cb0eab2024-12-08T06:13:42ZengElsevierTetrahedron Green Chem2773-22312024-12-014100056Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under lightShiqian Zhang0Quansheng Mou1Bowen Cao2Tongyu Han3Mingxin Liu4State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, ChinaState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, ChinaState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, ChinaState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, ChinaCorresponding author.; State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, ChinaCarbonyl compounds are widely found in various chemical reactions and natural products. Herein, a light-driven carbonylative cross-coupling reaction of bromobenzene was reported. Co2(CO)8 was used as an abundant solid carbonyl source to synthesize various Michael addition products with high yields. This reaction has broad substrates scope with good functional group tolerance. The mechanism study indicated that the reaction is achieved by the formation of benzoyl radical from homolytic C–Co cleavage under irradiation.http://www.sciencedirect.com/science/article/pii/S2773223124000219Michael additionCarbonylative cross couplingAryl bromidePhotochemistry |
| spellingShingle | Shiqian Zhang Quansheng Mou Bowen Cao Tongyu Han Mingxin Liu Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light Tetrahedron Green Chem Michael addition Carbonylative cross coupling Aryl bromide Photochemistry |
| title | Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light |
| title_full | Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light |
| title_fullStr | Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light |
| title_full_unstemmed | Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light |
| title_short | Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light |
| title_sort | three component carbonylative michael addition of aryl bromides using abundant metal carbonyl under light |
| topic | Michael addition Carbonylative cross coupling Aryl bromide Photochemistry |
| url | http://www.sciencedirect.com/science/article/pii/S2773223124000219 |
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