Predictive Application Value of Metagenomic Next-Generation Sequencing in the Resistance of Carbapenem-Resistant Enterobacteriaceae

Conclusion: mNGS demonstrated high sensitivity in predicting the presence of carbapenemase resistance genes in CRE, showing potential in early indication of isolate resistance information, thereby facilitating timely guidance for clinical treatment strategies.

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Main Authors: Jiacheng Tian, Chengtan Wang, Pingping Song, Zhiqing You, Xiuqin Jia, Xuan Li, Feng Pang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/cjid/6619016
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author Jiacheng Tian
Chengtan Wang
Pingping Song
Zhiqing You
Xiuqin Jia
Xuan Li
Feng Pang
author_facet Jiacheng Tian
Chengtan Wang
Pingping Song
Zhiqing You
Xiuqin Jia
Xuan Li
Feng Pang
author_sort Jiacheng Tian
collection DOAJ
description Conclusion: mNGS demonstrated high sensitivity in predicting the presence of carbapenemase resistance genes in CRE, showing potential in early indication of isolate resistance information, thereby facilitating timely guidance for clinical treatment strategies.
format Article
id doaj-art-4ccd5c47bbba40afbe7e259717bb8ba6
institution Kabale University
issn 1918-1493
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-4ccd5c47bbba40afbe7e259717bb8ba62025-01-14T00:00:02ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932025-01-01202510.1155/cjid/6619016Predictive Application Value of Metagenomic Next-Generation Sequencing in the Resistance of Carbapenem-Resistant EnterobacteriaceaeJiacheng Tian0Chengtan Wang1Pingping Song2Zhiqing You3Xiuqin Jia4Xuan Li5Feng Pang6Department of Clinical LaboratoryDepartment of Clinical LaboratoryDepartment of Clinical LaboratoryDepartment of Clinical LaboratoryThe Key Laboratory of Molecular PharmacologyThe Key Laboratory of Molecular PharmacologyDepartment of Clinical LaboratoryConclusion: mNGS demonstrated high sensitivity in predicting the presence of carbapenemase resistance genes in CRE, showing potential in early indication of isolate resistance information, thereby facilitating timely guidance for clinical treatment strategies.http://dx.doi.org/10.1155/cjid/6619016
spellingShingle Jiacheng Tian
Chengtan Wang
Pingping Song
Zhiqing You
Xiuqin Jia
Xuan Li
Feng Pang
Predictive Application Value of Metagenomic Next-Generation Sequencing in the Resistance of Carbapenem-Resistant Enterobacteriaceae
Canadian Journal of Infectious Diseases and Medical Microbiology
title Predictive Application Value of Metagenomic Next-Generation Sequencing in the Resistance of Carbapenem-Resistant Enterobacteriaceae
title_full Predictive Application Value of Metagenomic Next-Generation Sequencing in the Resistance of Carbapenem-Resistant Enterobacteriaceae
title_fullStr Predictive Application Value of Metagenomic Next-Generation Sequencing in the Resistance of Carbapenem-Resistant Enterobacteriaceae
title_full_unstemmed Predictive Application Value of Metagenomic Next-Generation Sequencing in the Resistance of Carbapenem-Resistant Enterobacteriaceae
title_short Predictive Application Value of Metagenomic Next-Generation Sequencing in the Resistance of Carbapenem-Resistant Enterobacteriaceae
title_sort predictive application value of metagenomic next generation sequencing in the resistance of carbapenem resistant enterobacteriaceae
url http://dx.doi.org/10.1155/cjid/6619016
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AT pingpingsong predictiveapplicationvalueofmetagenomicnextgenerationsequencingintheresistanceofcarbapenemresistantenterobacteriaceae
AT zhiqingyou predictiveapplicationvalueofmetagenomicnextgenerationsequencingintheresistanceofcarbapenemresistantenterobacteriaceae
AT xiuqinjia predictiveapplicationvalueofmetagenomicnextgenerationsequencingintheresistanceofcarbapenemresistantenterobacteriaceae
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