Multimodality imaging of bone marrow involvement in paediatric oncology
Identifying bone marrow involvement (with or without bone destruction) in children with cancer is essential for adequate diagnosis, prognostication, therapy planning, and response assessment. Imaging plays an increasing role, with MRI including DWI and [18F]FDG-PET/CT as the most commonly used imagi...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | EJC Paediatric Oncology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772610X2400045X |
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| author | Rutger A.J. Nievelstein Lise Borgwardt Thekla von Kalle Annemieke S. Littooij Lil-Sofie Ording Müller Nelleke Tolboom |
| author_facet | Rutger A.J. Nievelstein Lise Borgwardt Thekla von Kalle Annemieke S. Littooij Lil-Sofie Ording Müller Nelleke Tolboom |
| author_sort | Rutger A.J. Nievelstein |
| collection | DOAJ |
| description | Identifying bone marrow involvement (with or without bone destruction) in children with cancer is essential for adequate diagnosis, prognostication, therapy planning, and response assessment. Imaging plays an increasing role, with MRI including DWI and [18F]FDG-PET/CT as the most commonly used imaging techniques. Interpretation of the paediatric bone marrow on imaging might be challenging because of age-related physiological changes in the bone marrow, as well as disease and therapy related effects. In this review, we discuss how the imaging techniques available may be employed to detect bone marrow involvement (BMI) in paediatric oncology. Furthermore, insights into physiological, disease and therapy related bone marrow changes in children that might influence bone marrow imaging interpretation will be provided. |
| format | Article |
| id | doaj-art-4cc8b87f6b604a1bbc247dc3eeba2404 |
| institution | Kabale University |
| issn | 2772-610X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | EJC Paediatric Oncology |
| spelling | doaj-art-4cc8b87f6b604a1bbc247dc3eeba24042024-12-13T11:08:30ZengElsevierEJC Paediatric Oncology2772-610X2024-12-014100185Multimodality imaging of bone marrow involvement in paediatric oncologyRutger A.J. Nievelstein0Lise Borgwardt1Thekla von Kalle2Annemieke S. Littooij3Lil-Sofie Ording Müller4Nelleke Tolboom5Department of Radiology & Nuclear Medicine, UMC Utrecht/Wilhelmina Children’s Hospital, and Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Correspondence to: Department of Radiology & Nuclear Medicine, Division Imaging & Oncology, UMC Utrecht/Wilhelmina Children’s Hospital, P.O. Box 85500, Utrecht, GA 3508, the Netherlands.Department of Clinical Physiology and Nuclear medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, DenmarkRadiological Institute Olgahospital, Klinikum Stuttgart, Stuttgart, GermanyDepartment of Radiology & Nuclear Medicine, UMC Utrecht/Wilhelmina Children’s Hospital, and Princess Máxima Center for Pediatric Oncology, Utrecht, the NetherlandsDivision of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, NorwayDepartment of Radiology & Nuclear Medicine, UMC Utrecht/Wilhelmina Children’s Hospital, and Princess Máxima Center for Pediatric Oncology, Utrecht, the NetherlandsIdentifying bone marrow involvement (with or without bone destruction) in children with cancer is essential for adequate diagnosis, prognostication, therapy planning, and response assessment. Imaging plays an increasing role, with MRI including DWI and [18F]FDG-PET/CT as the most commonly used imaging techniques. Interpretation of the paediatric bone marrow on imaging might be challenging because of age-related physiological changes in the bone marrow, as well as disease and therapy related effects. In this review, we discuss how the imaging techniques available may be employed to detect bone marrow involvement (BMI) in paediatric oncology. Furthermore, insights into physiological, disease and therapy related bone marrow changes in children that might influence bone marrow imaging interpretation will be provided.http://www.sciencedirect.com/science/article/pii/S2772610X2400045XMultimodality imagingPaediatric radiologyMRIPETBone marrowBone marrow involvement |
| spellingShingle | Rutger A.J. Nievelstein Lise Borgwardt Thekla von Kalle Annemieke S. Littooij Lil-Sofie Ording Müller Nelleke Tolboom Multimodality imaging of bone marrow involvement in paediatric oncology EJC Paediatric Oncology Multimodality imaging Paediatric radiology MRI PET Bone marrow Bone marrow involvement |
| title | Multimodality imaging of bone marrow involvement in paediatric oncology |
| title_full | Multimodality imaging of bone marrow involvement in paediatric oncology |
| title_fullStr | Multimodality imaging of bone marrow involvement in paediatric oncology |
| title_full_unstemmed | Multimodality imaging of bone marrow involvement in paediatric oncology |
| title_short | Multimodality imaging of bone marrow involvement in paediatric oncology |
| title_sort | multimodality imaging of bone marrow involvement in paediatric oncology |
| topic | Multimodality imaging Paediatric radiology MRI PET Bone marrow Bone marrow involvement |
| url | http://www.sciencedirect.com/science/article/pii/S2772610X2400045X |
| work_keys_str_mv | AT rutgerajnievelstein multimodalityimagingofbonemarrowinvolvementinpaediatriconcology AT liseborgwardt multimodalityimagingofbonemarrowinvolvementinpaediatriconcology AT theklavonkalle multimodalityimagingofbonemarrowinvolvementinpaediatriconcology AT annemiekeslittooij multimodalityimagingofbonemarrowinvolvementinpaediatriconcology AT lilsofieordingmuller multimodalityimagingofbonemarrowinvolvementinpaediatriconcology AT nelleketolboom multimodalityimagingofbonemarrowinvolvementinpaediatriconcology |