Evaluation of the Effects of Age, Sex, and Dexpanthenol-Containing Skin Care on the Facial and Body Skin Microbiome

Given the pivotal role played by the microbiome in skin health, it is important to understand how its composition varies with age, sex, and body site and regular use of topical products. Four studies were carried out to determine the effects of long-term (4-week) use of different dexpanthenol-contai...

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Main Authors: Zainab Qaizar, Raffaella de Salvo, Gregor Bieri, Katrin Unbereit, Shannon Montgomery, Erwan Peltier
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cosmetics
Subjects:
Online Access:https://www.mdpi.com/2079-9284/11/6/213
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author Zainab Qaizar
Raffaella de Salvo
Gregor Bieri
Katrin Unbereit
Shannon Montgomery
Erwan Peltier
author_facet Zainab Qaizar
Raffaella de Salvo
Gregor Bieri
Katrin Unbereit
Shannon Montgomery
Erwan Peltier
author_sort Zainab Qaizar
collection DOAJ
description Given the pivotal role played by the microbiome in skin health, it is important to understand how its composition varies with age, sex, and body site and regular use of topical products. Four studies were carried out to determine the effects of long-term (4-week) use of different dexpanthenol-containing topical products on the skin microbiome of a varied population with cosmetically dry skin. The skin microbiome composition was assessed before and after product usage. No significant changes in microbiome richness or diversity were found for the individual test products; however, a meta-analysis of the combined dataset did show changes in microbiome composition as a function of the subject’s sex, age, and body site. The work presented here demonstrates how the use of carefully formulated topical products on skin, when used in a way that is representative of real-life usage conditions, can respect the microbial diversity present on skin across a widely varied study population.
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issn 2079-9284
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publishDate 2024-12-01
publisher MDPI AG
record_format Article
series Cosmetics
spelling doaj-art-4c8b4996f0534c5aa6aae212a09d52dc2024-12-27T14:19:23ZengMDPI AGCosmetics2079-92842024-12-0111621310.3390/cosmetics11060213Evaluation of the Effects of Age, Sex, and Dexpanthenol-Containing Skin Care on the Facial and Body Skin MicrobiomeZainab Qaizar0Raffaella de Salvo1Gregor Bieri2Katrin Unbereit3Shannon Montgomery4Erwan Peltier5Bayer B.V., Hoofddorp, Siriusdreef 36, 2132 WT Hoofddorp, The NetherlandsBayer Consumer Care AG, Peter Merian Straße 84, 4052 Basel, SwitzerlandBayer Consumer Care AG, Peter Merian Straße 84, 4052 Basel, SwitzerlandSGS proderm GmbH, Kiebitzweg 2, 22869 Schenefeld, GermanyCapgemini Engineering Deutschland S.A.S. & Co. KG, 10559 Berlin, GermanyBayer Consumer Care AG, Peter Merian Straße 84, 4052 Basel, SwitzerlandGiven the pivotal role played by the microbiome in skin health, it is important to understand how its composition varies with age, sex, and body site and regular use of topical products. Four studies were carried out to determine the effects of long-term (4-week) use of different dexpanthenol-containing topical products on the skin microbiome of a varied population with cosmetically dry skin. The skin microbiome composition was assessed before and after product usage. No significant changes in microbiome richness or diversity were found for the individual test products; however, a meta-analysis of the combined dataset did show changes in microbiome composition as a function of the subject’s sex, age, and body site. The work presented here demonstrates how the use of carefully formulated topical products on skin, when used in a way that is representative of real-life usage conditions, can respect the microbial diversity present on skin across a widely varied study population.https://www.mdpi.com/2079-9284/11/6/213microbiometopical productsskin healthdexpanthenol
spellingShingle Zainab Qaizar
Raffaella de Salvo
Gregor Bieri
Katrin Unbereit
Shannon Montgomery
Erwan Peltier
Evaluation of the Effects of Age, Sex, and Dexpanthenol-Containing Skin Care on the Facial and Body Skin Microbiome
Cosmetics
microbiome
topical products
skin health
dexpanthenol
title Evaluation of the Effects of Age, Sex, and Dexpanthenol-Containing Skin Care on the Facial and Body Skin Microbiome
title_full Evaluation of the Effects of Age, Sex, and Dexpanthenol-Containing Skin Care on the Facial and Body Skin Microbiome
title_fullStr Evaluation of the Effects of Age, Sex, and Dexpanthenol-Containing Skin Care on the Facial and Body Skin Microbiome
title_full_unstemmed Evaluation of the Effects of Age, Sex, and Dexpanthenol-Containing Skin Care on the Facial and Body Skin Microbiome
title_short Evaluation of the Effects of Age, Sex, and Dexpanthenol-Containing Skin Care on the Facial and Body Skin Microbiome
title_sort evaluation of the effects of age sex and dexpanthenol containing skin care on the facial and body skin microbiome
topic microbiome
topical products
skin health
dexpanthenol
url https://www.mdpi.com/2079-9284/11/6/213
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