Blast‐Overpressure Induced Modulation of PARP‐SIRT‐NRF2 Axis in Stress Signaling of Astrocytes and Microglia

Blast‐Overpressure Induced Modulation of PARP‐SIRT‐NRF2 Axis in Stress Signaling of Astrocytes and Microglia

ABSTRACT Background The pathomechanism of blast traumatic brain injury (TBI) and blunt TBI is different. In blast injury, evidence indicates that a single blast exposure can often manifest long‐term neurological impairments. However, its pathomechanism is still elusive, and treatments have been symp...

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Bibliographic Details
Main Authors: Vijaya Prakash Krishnan Muthaiah, Kathiravan Kaliyappan, Ramkumar Thiayagarajan, Supriya Mahajan, Krishnamoorthy Gunasekaran
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Immunity, Inflammation and Disease
Subjects:
ATP
blast‐overpressure
Glia
poly ADP‐ribose polymerase
sirtuins
Online Access:https://doi.org/10.1002/iid3.70106
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