DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.

Proper development of the immune system is an intricate process dependent on many factors, including an intact DNA damage response. The DNA double-strand break signaling kinase ATM and its cofactor NBS1 are required during T cell development and for the maintenance of genomic stability. The role of...

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Main Authors: Jana Prochazkova, Shinya Sakaguchi, Michel Owusu, Abdelghani Mazouzi, Marc Wiedner, Georgia Velimezi, Martin Moder, Gleb Turchinovich, Anastasiya Hladik, Elisabeth Gurnhofer, Adrian Hayday, Axel Behrens, Sylvia Knapp, Lukas Kenner, Wilfried Ellmeier, Joanna I Loizou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1005645
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