Widespread genomic de novo DNA methylation occurs following CD8+ T cell activation and proliferation

Widespread genomic de novo DNA methylation occurs following CD8+ T cell activation and proliferation

This research investigates the intricate dynamics of DNA methylation in the hours following CD8+ T cell activation, during a critical yet understudied temporal window. DNA methylation is an epigenetic modification central to regulation of gene expression and directing immune responses. Our investiga...

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Bibliographic Details
Main Authors: Annika R. Seddon, Olivia M. Damiano, Mark B. Hampton, Aaron J. Stevens
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Epigenetics
Subjects:
T-cell epigenetics
inflammation
redox biology
DNA methylation
oxidants
differentiation
Online Access:https://www.tandfonline.com/doi/10.1080/15592294.2024.2367385
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