An analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorption
Spontaneous resorption of lumbar disc herniation (RLDH) is a frequently observed phenomenon in imaging studies. However, the predictors of this process are difficult to control, posing a major clinical challenge. Moreover, the underlying biological mechanisms of RLDH remain incompletely understood....
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| Format: | Article |
| Language: | English |
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Forum Multimedia Publishing LLC
2025-04-01
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| Series: | European Cells & Materials |
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| Online Access: | https://www.ecmjournal.org/papers/vol050/vol050a08.php |
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| _version_ | 1850274156738772992 |
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| author | L You ZY Xiao Y Yang L Pei HS Jing GQ Chen |
| author_facet | L You ZY Xiao Y Yang L Pei HS Jing GQ Chen |
| author_sort | L You |
| collection | DOAJ |
| description | Spontaneous resorption of lumbar disc herniation (RLDH) is a frequently observed phenomenon in imaging studies. However, the predictors of this process are difficult to control, posing a major clinical challenge. Moreover, the underlying biological mechanisms of RLDH remain incompletely understood. This limitation hinders clinicians from optimizing non-surgical treatments of lumbar disc herniation (LDH) in clinical practice. This review summarized the existing literature on the resorption of LDH, aiming to elucidate the predictive factors and potential biomechanical processes underlying this disease. Additionally, existing therapeutic approaches designed to promote resorption were also summarized. By providing insights into the dynamics of LDH resorption, this review offers the possibility of enhancing diagnostic accuracy and facilitating the development of targeted treatment strategies. |
| format | Article |
| id | doaj-art-4c6ea3713a0c4e9a8d3a1f4fe774d32a |
| institution | OA Journals |
| issn | 1473-2262 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Forum Multimedia Publishing LLC |
| record_format | Article |
| series | European Cells & Materials |
| spelling | doaj-art-4c6ea3713a0c4e9a8d3a1f4fe774d32a2025-08-20T01:51:13ZengForum Multimedia Publishing LLCEuropean Cells & Materials1473-22622025-04-015012413610.22203/eCM.v050a08An analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorptionL YouZY XiaoY YangL PeiHS JingGQ ChenSpontaneous resorption of lumbar disc herniation (RLDH) is a frequently observed phenomenon in imaging studies. However, the predictors of this process are difficult to control, posing a major clinical challenge. Moreover, the underlying biological mechanisms of RLDH remain incompletely understood. This limitation hinders clinicians from optimizing non-surgical treatments of lumbar disc herniation (LDH) in clinical practice. This review summarized the existing literature on the resorption of LDH, aiming to elucidate the predictive factors and potential biomechanical processes underlying this disease. Additionally, existing therapeutic approaches designed to promote resorption were also summarized. By providing insights into the dynamics of LDH resorption, this review offers the possibility of enhancing diagnostic accuracy and facilitating the development of targeted treatment strategies.https://www.ecmjournal.org/papers/vol050/vol050a08.phplumbar disc herniationresorptionmechanismspredictive factorsmacrophages |
| spellingShingle | L You ZY Xiao Y Yang L Pei HS Jing GQ Chen An analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorption European Cells & Materials lumbar disc herniation resorption mechanisms predictive factors macrophages |
| title | An analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorption |
| title_full | An analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorption |
| title_fullStr | An analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorption |
| title_full_unstemmed | An analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorption |
| title_short | An analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorption |
| title_sort | analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorption |
| topic | lumbar disc herniation resorption mechanisms predictive factors macrophages |
| url | https://www.ecmjournal.org/papers/vol050/vol050a08.php |
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