FTO-mediated SMAD2 m6A modification protects cartilage against Osteoarthritis

FTO-mediated SMAD2 m6A modification protects cartilage against Osteoarthritis

Abstract N6-methyladenosine (m6A) modification is one of the most prevalent forms of epigenetic modification and plays an important role in the development of degenerative diseases such as osteoarthritis (OA). However, the evidence concerning the role of m6A modification in OA is insufficient. Here,...

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Bibliographic Details
Main Authors: Hongyi Zhou, Ziang Xie, Yu Qian, Weiyu Ni, Lei Cui, Xiangqian Fang, Shuanglin Wan, Xiangde Zhao, An Qin, Shunwu Fan, Yizheng Wu
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01330-y
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