SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21CIPI, cyclin D1 and β‐catenin

SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21CIPI, cyclin D1 and β‐catenin

The Sry‐related high‐mobility group box6 (SOX6) has been implicated in the development of cancer, but its role in lung cancer is incompletely understood. Here, we report that SOX6 expression is frequently down‐regulated in lung adenocarcinoma tissues. Moreover, SOX6 can inhibit the proliferation and...

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Bibliographic Details
Main Authors: Liyan Lv, Min Zhou, Jian Zhang, Fang Liu, Li Qi, Shuai Zhang, Yi Bi, Yan Yu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:FEBS Open Bio
Subjects:
β‐catenin
cyclin D1
lung adenocarcinoma
p21CIPI
p53
SOX6
Online Access:https://doi.org/10.1002/2211-5463.12762
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