Association between single nucleotide polymorphisms of DNA repair genes (BRCA1, BRCA2, and PALB2) and breast cancer incidence in a subset of Iranian population

Abstract Background Breast cancer (BC) is the most common malignancy among Iranian females, accounting for 24.4% of all malignancies. Germ line mutations in DNA repair system-related genes are associated with an increased risk of BC. This study aims to evaluate the frequencies of single nucleotide p...

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Bibliographic Details
Main Authors: Sepideh Jahangiri, Zahra Abdan, Massoud Houshmand, Ali Souroush, Mozaffar Aznab
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:https://doi.org/10.1186/s13053-025-00311-0
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