Deletion of MAPL ameliorates septic cardiomyopathy by mitigating mitochondrial dysfunction

Deletion of MAPL ameliorates septic cardiomyopathy by mitigating mitochondrial dysfunction

Abstract Aim Mitochondrial dysfunction is a critical factor in the pathogenesis of septic cardiomyopathy (SCM). Mitochondrial anchored protein ligase (MAPL), a small ubiquitin-like modifier (SUMO) E3 ligase, plays a significant role in mitochondrial function. However, the role of MAPL in SCM remains...

Full description

Saved in:
Bibliographic Details
Main Authors: Yinghua Wang, Xiying Huang, Huanhuan Huo, Zhaohua Cai, Qingqi Ji, Yi Jiang, Fei Zhuang, Yi Li, Linghong Shen, Xia Wang, Ben He
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
MAPL
Mitochondria
SUMOylation
Septic cardiomyopathy
Online Access:https://doi.org/10.1186/s12967-024-05836-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12967-024-05836-x

Similar Items