Metformin and berberine synergistically improve NAFLD via the AMPK–SREBP1–FASN signaling pathway

Abstract Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic condition linked to dyslipidemia, insulin resistance, and persistent inflammation. Due to its complex pathogenesis, no approved pharmacological treatments currently exist. The research sought to explore the combined impact of...

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Bibliographic Details
Main Authors: Na Li, Quan-wei Chen, Xiao-long Gong, Fang Liu, Bin Zhang, Qi-shen Wang, Hao Zhang, Jian-jun Han
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-15495-7
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