Modeling of pharmacokinetic/pharmacodynamic parameters in regular intermittent intravenous infusion and translational application of the models in personalized antibiotics dosing
Abstract Objective Quantitative calculation models for the ratio of daily area under the concentration–time curve (AUC24) to the minimum inhibitory concentration (MIC) (i.e., AUC24/MIC) and the amount of time that concentration stays above the MIC during a dosing interval (i.e., T>MIC%) in regula...
Saved in:
| Main Author: | Xiangqing Song |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
|
| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-025-06832-5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Pharmacokinetic and pharmacodynamic characterization of remimazolam in older Japanese adults who underwent general anesthesia at early stage of infusion
by: Satoshi Ueshima, et al.
Published: (2025-07-01) -
High-resolution fecal pharmacokinetic modeling in mice with orally administered antibiotics
by: Rie Maskawa, et al.
Published: (2025-07-01) -
COMPARISON OF PHARMACOKINETICS AND PHARMACODYNAMICS OF THE ORIGINAL AND GENERIC ENALAPRIL IN THE ELDERLY PATIENTS WITH ARTERIAL HYPERTENSION
by: O. P. Bobrova, et al.
Published: (2015-12-01) -
Pharmacodynamics, pharmacokinetics, interactions with other drugs, toxicity and clinical effectiveness of proton pump inhibitors
by: Łukasz Wołowiec, et al.
Published: (2025-07-01) -
Pharmacokinetic and pharmacodynamic integration and resistance analysis of cefquinome against Streptococcus uberis in vitro dynamic model
by: Chongyang Li, et al.
Published: (2025-07-01)