Modeling of pharmacokinetic/pharmacodynamic parameters in regular intermittent intravenous infusion and translational application of the models in personalized antibiotics dosing

Abstract Objective Quantitative calculation models for the ratio of daily area under the concentration–time curve (AUC24) to the minimum inhibitory concentration (MIC) (i.e., AUC24/MIC) and the amount of time that concentration stays above the MIC during a dosing interval (i.e., T>MIC%) in regula...

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Bibliographic Details
Main Author: Xiangqing Song
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06832-5
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