Parasitic infections: A new frontier for PGD2 functions
Prostaglandin (PG)D2 is produced and/or triggered by different parasites to modulate the course of the infection. These findings position PGD2 as a therapeutic target and suggest potential beneficial effects of repositioned drugs that target its synthesis or receptor engagement. However, recent in v...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Current Research in Immunology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590255524000027 |
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| _version_ | 1846139836684042240 |
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| author | Bruno L. Diaz Christianne Bandeira-Melo |
| author_facet | Bruno L. Diaz Christianne Bandeira-Melo |
| author_sort | Bruno L. Diaz |
| collection | DOAJ |
| description | Prostaglandin (PG)D2 is produced and/or triggered by different parasites to modulate the course of the infection. These findings position PGD2 as a therapeutic target and suggest potential beneficial effects of repositioned drugs that target its synthesis or receptor engagement. However, recent in vivo data may suggest a more nuanced role and warrants further investigation of the role of PGD2 during the full course and complexity of parasitic infections. |
| format | Article |
| id | doaj-art-4b06c95cf7a24ae8b23b53c3b6dcc762 |
| institution | Kabale University |
| issn | 2590-2555 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Current Research in Immunology |
| spelling | doaj-art-4b06c95cf7a24ae8b23b53c3b6dcc7622024-12-06T05:14:28ZengElsevierCurrent Research in Immunology2590-25552024-01-015100078Parasitic infections: A new frontier for PGD2 functionsBruno L. Diaz0Christianne Bandeira-Melo1Corresponding author.; Laboratório de Inflamação, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho 373, Cidade Universitária, Rio de Janeiro, RJ, 21941-902, BrazilCorresponding author.; Laboratório de Inflamação, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho 373, Cidade Universitária, Rio de Janeiro, RJ, 21941-902, BrazilProstaglandin (PG)D2 is produced and/or triggered by different parasites to modulate the course of the infection. These findings position PGD2 as a therapeutic target and suggest potential beneficial effects of repositioned drugs that target its synthesis or receptor engagement. However, recent in vivo data may suggest a more nuanced role and warrants further investigation of the role of PGD2 during the full course and complexity of parasitic infections.http://www.sciencedirect.com/science/article/pii/S2590255524000027 |
| spellingShingle | Bruno L. Diaz Christianne Bandeira-Melo Parasitic infections: A new frontier for PGD2 functions Current Research in Immunology |
| title | Parasitic infections: A new frontier for PGD2 functions |
| title_full | Parasitic infections: A new frontier for PGD2 functions |
| title_fullStr | Parasitic infections: A new frontier for PGD2 functions |
| title_full_unstemmed | Parasitic infections: A new frontier for PGD2 functions |
| title_short | Parasitic infections: A new frontier for PGD2 functions |
| title_sort | parasitic infections a new frontier for pgd2 functions |
| url | http://www.sciencedirect.com/science/article/pii/S2590255524000027 |
| work_keys_str_mv | AT brunoldiaz parasiticinfectionsanewfrontierforpgd2functions AT christiannebandeiramelo parasiticinfectionsanewfrontierforpgd2functions |