Insulin Therapy: “When Saviour Turns Hostile”
Insulin is the cornerstone of type 1 diabetes mellitus (T1DM) treatment. Insulin allergy in patients with T1DM on insulin is an uncommon problem that might manifest itself as immediate or delayed symptoms after injections. We present 2 cases: the first is a 17-year-old girl who was diagnosed with T1...
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| Format: | Article |
| Language: | English |
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Knowledge E
2022-03-01
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| Series: | Dubai Diabetes and Endocrinology Journal |
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| Online Access: | https://www.karger.com/Article/FullText/522562 |
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| author | Dhanya Soodhana Mohan Vani Hebbal Nagarajappa Santhosh Olety Sathyanarayana Sahana M. Srinivas Raghupathy Palany |
| author_facet | Dhanya Soodhana Mohan Vani Hebbal Nagarajappa Santhosh Olety Sathyanarayana Sahana M. Srinivas Raghupathy Palany |
| author_sort | Dhanya Soodhana Mohan |
| collection | DOAJ |
| description | Insulin is the cornerstone of type 1 diabetes mellitus (T1DM) treatment. Insulin allergy in patients with T1DM on insulin is an uncommon problem that might manifest itself as immediate or delayed symptoms after injections. We present 2 cases: the first is a 17-year-old girl who was diagnosed with T1DM at the age of 14 and has had several skin lesions at injection sites over the past 2 months that have not responded to antibiotics. The second case involves a 4-year-old boy who was diagnosed with T1DM at the age of 15 months and had non-tender, erythematous, and indurated lesions. Insulin hypersensitivity was detected in both cases, thus newer analogues were administered instead of regular and isophane insulin, and the lesions dramatically reduced. |
| format | Article |
| id | doaj-art-4afb9822bbd54d4a82727e5b41bed4e4 |
| institution | Kabale University |
| issn | 2673-1797 2673-1738 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Dubai Diabetes and Endocrinology Journal |
| spelling | doaj-art-4afb9822bbd54d4a82727e5b41bed4e42024-12-02T06:09:15ZengKnowledge EDubai Diabetes and Endocrinology Journal2673-17972673-17382022-03-011410.1159/000522562522562Insulin Therapy: “When Saviour Turns Hostile”Dhanya Soodhana Mohan0Vani Hebbal Nagarajappa1Santhosh Olety Sathyanarayana2Sahana M. Srinivas3Raghupathy Palany4https://orcid.org/0000-0002-7448-586XDepartment of Pediatric and Adolescent Endocrinology, Indira Gandhi Institute of Child Health, Bangalore, IndiaDepartment of Pediatric and Adolescent Endocrinology, Indira Gandhi Institute of Child Health, Bangalore, IndiaKarnataka Institute of Endocrinology and Research, Bangalore, IndiaDepartment of Pediatric Dermatology, Indira Gandhi Institute of Child Health, Bangalore, IndiaDepartment of Pediatric and Adolescent Endocrinology, Indira Gandhi Institute of Child Health, Bangalore, IndiaInsulin is the cornerstone of type 1 diabetes mellitus (T1DM) treatment. Insulin allergy in patients with T1DM on insulin is an uncommon problem that might manifest itself as immediate or delayed symptoms after injections. We present 2 cases: the first is a 17-year-old girl who was diagnosed with T1DM at the age of 14 and has had several skin lesions at injection sites over the past 2 months that have not responded to antibiotics. The second case involves a 4-year-old boy who was diagnosed with T1DM at the age of 15 months and had non-tender, erythematous, and indurated lesions. Insulin hypersensitivity was detected in both cases, thus newer analogues were administered instead of regular and isophane insulin, and the lesions dramatically reduced.https://www.karger.com/Article/FullText/522562diabetes mellitusinsulinhypersensitivity reactions |
| spellingShingle | Dhanya Soodhana Mohan Vani Hebbal Nagarajappa Santhosh Olety Sathyanarayana Sahana M. Srinivas Raghupathy Palany Insulin Therapy: “When Saviour Turns Hostile” Dubai Diabetes and Endocrinology Journal diabetes mellitus insulin hypersensitivity reactions |
| title | Insulin Therapy: “When Saviour Turns Hostile” |
| title_full | Insulin Therapy: “When Saviour Turns Hostile” |
| title_fullStr | Insulin Therapy: “When Saviour Turns Hostile” |
| title_full_unstemmed | Insulin Therapy: “When Saviour Turns Hostile” |
| title_short | Insulin Therapy: “When Saviour Turns Hostile” |
| title_sort | insulin therapy when saviour turns hostile |
| topic | diabetes mellitus insulin hypersensitivity reactions |
| url | https://www.karger.com/Article/FullText/522562 |
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