The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy
Currently, approaches to personalized medicine are actively developing. For example, the use of platelet-rich plasma (PRP) is actively growing every year. As a result of activation, platelets release a wide range of growth factors, cytokines, chemokines, and angiogenic factors, after which these mol...
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MDPI AG
2024-10-01
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| author | Anna V. Gorodilova Chulpan B. Kharisova Maria N. Osinnikova Kristina V. Kitaeva Ivan Y. Filin Yuriy P. Mayasin Valeriya V. Solovyeva Albert A. Rizvanov |
| author_facet | Anna V. Gorodilova Chulpan B. Kharisova Maria N. Osinnikova Kristina V. Kitaeva Ivan Y. Filin Yuriy P. Mayasin Valeriya V. Solovyeva Albert A. Rizvanov |
| author_sort | Anna V. Gorodilova |
| collection | DOAJ |
| description | Currently, approaches to personalized medicine are actively developing. For example, the use of platelet-rich plasma (PRP) is actively growing every year. As a result of activation, platelets release a wide range of growth factors, cytokines, chemokines, and angiogenic factors, after which these molecules regulate chemotaxis, inflammation, and vasomotor function and play a crucial role in restoring the integrity of damaged vascular walls, angiogenesis, and tissue regeneration. Due to these characteristics, PRP has a wide potential in regenerative medicine and gerontology. PRP products are actively used not only in esthetic medicine but also to stimulate tissue regeneration and relieve chronic inflammation. PRP therapy has a number of advantages, but the controversial results of clinical studies, a lack of standardization of the sample preparation of the material, and insufficient objective data on the evaluation of efficacy do not allow us to unambiguously look at the use of PRP for therapeutic purposes. In this review, we will examine the current clinical efficacy of PRP-based products and analyze the contribution of PRP in the therapy of diseases associated with aging. |
| format | Article |
| id | doaj-art-4adf05e93cad46d58d75f649329ca4a7 |
| institution | Kabale University |
| issn | 2073-4409 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj-art-4adf05e93cad46d58d75f649329ca4a72024-11-08T14:34:24ZengMDPI AGCells2073-44092024-10-011321175510.3390/cells13211755The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging TherapyAnna V. Gorodilova0Chulpan B. Kharisova1Maria N. Osinnikova2Kristina V. Kitaeva3Ivan Y. Filin4Yuriy P. Mayasin5Valeriya V. Solovyeva6Albert A. Rizvanov7Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, RussiaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, RussiaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, RussiaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, RussiaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, RussiaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, RussiaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, RussiaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, RussiaCurrently, approaches to personalized medicine are actively developing. For example, the use of platelet-rich plasma (PRP) is actively growing every year. As a result of activation, platelets release a wide range of growth factors, cytokines, chemokines, and angiogenic factors, after which these molecules regulate chemotaxis, inflammation, and vasomotor function and play a crucial role in restoring the integrity of damaged vascular walls, angiogenesis, and tissue regeneration. Due to these characteristics, PRP has a wide potential in regenerative medicine and gerontology. PRP products are actively used not only in esthetic medicine but also to stimulate tissue regeneration and relieve chronic inflammation. PRP therapy has a number of advantages, but the controversial results of clinical studies, a lack of standardization of the sample preparation of the material, and insufficient objective data on the evaluation of efficacy do not allow us to unambiguously look at the use of PRP for therapeutic purposes. In this review, we will examine the current clinical efficacy of PRP-based products and analyze the contribution of PRP in the therapy of diseases associated with aging.https://www.mdpi.com/2073-4409/13/21/1755platelet-rich plasmaplateletregenerative medicineaging |
| spellingShingle | Anna V. Gorodilova Chulpan B. Kharisova Maria N. Osinnikova Kristina V. Kitaeva Ivan Y. Filin Yuriy P. Mayasin Valeriya V. Solovyeva Albert A. Rizvanov The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy Cells platelet-rich plasma platelet regenerative medicine aging |
| title | The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy |
| title_full | The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy |
| title_fullStr | The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy |
| title_full_unstemmed | The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy |
| title_short | The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy |
| title_sort | well forgotten old platelet rich plasma in modern anti aging therapy |
| topic | platelet-rich plasma platelet regenerative medicine aging |
| url | https://www.mdpi.com/2073-4409/13/21/1755 |
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