High Ki67 expression, HER2 overexpression, and low progesterone receptor levels in high-grade DCIS: significant associations with clinical practice implications

High Ki67 expression, HER2 overexpression, and low progesterone receptor levels in high-grade DCIS: significant associations with clinical practice implications

Simple summaryWe investigated the role of Ki67, a ubiquitous marker in cancer, within the context of ductal carcinoma in situ (DCIS), a precursor of invasive breast cancer. Through rigorous analysis of histopathological and immunopathological samples from a substantial cohort, this study revealed ro...

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Bibliographic Details
Main Authors:	Hossein Schandiz, Lorant Farkas, Daehoon Park, Yan Liu, Solveig N. Andersen, Torill Sauer, Jürgen Geisler
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Oncology
Subjects:	ductal carcinoma in situ (DCIS) of the breast immunohistochemisty personalized medicine (PM) Ki67 proliferation index hormone receptors human epidermal growth factor receptor 2 (HER2) International Ki67 in Breast Cancer Working Group (IKWG)
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1467664/full
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