Tumor dynamics model with treatments by oncolytic virotherapy and MEK inhibitors involving TNF-α inhibitors: Stability analysis and optimal control

Oncolytic virotherapy is one of the cancer treatments that kills cancer cells but leaves normal cells. Furthermore, mitogen-activated protein kinase (MEK) inhibitors boost chimeric antigen receptor expression and increase oncolytic virus entry into tumor cells, and TNF-α{\rm{\alpha }} inhibitors imp...

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Bibliographic Details
Main Authors: Daengkongkho Salinthip, Viriyapong Ratchada
Format: Article
Language:English
Published: De Gruyter 2025-08-01
Series:Computational and Mathematical Biophysics
Subjects:
Online Access:https://doi.org/10.1515/cmb-2025-0025
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