Anti-inflammatory treatment using alpha melanocyte stimulating hormone (α-MSH) does not alter osteoblasts differentiation and fracture healing

Anti-inflammatory treatment using alpha melanocyte stimulating hormone (α-MSH) does not alter osteoblasts differentiation and fracture healing

Abstract Background Alpha-melanocyte-stimulating-hormone (α-MSH) has been identified as a new anti-inflammatory treatment compound in rheumatoid arthritis (RA) and other inflammatory diseases. However, its direct effect on bone cell differentiation or on bone regeneration, which is an inflammatory p...

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Bibliographic Details
Main Authors: Johanna Graue, Melanie Timmen, Katharina Schmitz, Daniel Kronenberg, Markus Böhm, Kishor K. Sivaraj, M. Gabriele Bixel, Richard Stange
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Musculoskeletal Disorders
Subjects:
Melanocortin receptor
Inflammation
Fracture healing
Osteoblast
Alpha-MSH
Online Access:https://doi.org/10.1186/s12891-025-08374-9
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