Molecular Dynamics Insights into Peptide-Based Tetrodotoxin Delivery Nanostructures

Molecular Dynamics Insights into Peptide-Based Tetrodotoxin Delivery Nanostructures

Tetrodotoxin (TTX), a potent Site-1 sodium channel blocker (S1SCB), offers highly effective local anesthetic properties with minimal addiction potential. To fully leverage TTX’s capabilities as a local anesthetic, it is crucial to develop a drug delivery system that balances its systemic toxicity wi...

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Bibliographic Details
Main Authors:	Shenghan Song, Xinyu Xia, Temair Shorty, Tongtong Li, Amy O. Stevens, Chao Zhao, Yi He
Format:	Article
Language:	English
Published:	MDPI AG 2024-12-01
Series:	Molecules
Subjects:	tetrodotoxin (TTX) Site-1 sodium channel blocker (S1SCB) local anesthetics peptide-based nanostructures sustained-release drug delivery molecular dynamics simulations
Online Access:	https://www.mdpi.com/1420-3049/30/1/61
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