Efficacy of music therapy as a non-pharmacological measure to support alzheimer's disease patients: a systematic review

Abstract Background Alzheimer's disease (AD) is a degenerative disease of the central nervous system characterized by progressive memory degradation and language and behavior disorders. Apart from curative pharmacological therapies, music therapy (MT) has been diffusely used as an efficient and...

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Main Authors: Jia Wang, Cong Liu, Ying Dai, Can Mei, Guiping Wang, Yong Wang, Tao Huang, Jianbo Zhan, Jing Cheng
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Geriatrics
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Online Access:https://doi.org/10.1186/s12877-025-06073-7
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author Jia Wang
Cong Liu
Ying Dai
Can Mei
Guiping Wang
Yong Wang
Tao Huang
Jianbo Zhan
Jing Cheng
author_facet Jia Wang
Cong Liu
Ying Dai
Can Mei
Guiping Wang
Yong Wang
Tao Huang
Jianbo Zhan
Jing Cheng
author_sort Jia Wang
collection DOAJ
description Abstract Background Alzheimer's disease (AD) is a degenerative disease of the central nervous system characterized by progressive memory degradation and language and behavior disorders. Apart from curative pharmacological therapies, music therapy (MT) has been diffusely used as an efficient and economical non-pharmacological treatment for AD patients in recent years. Methods Three databases (PubMed, Web of Science and PsycINFO) were searched to analyse the efficacy of MT in patients with AD. Keywords included "Alzheimer's disease", "AD", "Mild Cognitive Impairment", "MCI", "music" and "music therapy". Results Literatures between January 2013 and January 2023 were selected, with 42 literatures included in the study, which highlights the beneficial impact of MT on cognition (memory, attention, language), behavioural and psychological symptoms (anxiety, depression and agitation), quality of life, self-esteem and physical pain in AD patients. Conclusion MT is a promising non-pharmacological treatment approach for individuals living with AD. However, further evidences from prospective, randomised, blinded, uniform, and rigorous method-logical investigations in this field are required to conclusively validate MT's impact on this disease. PROSPERO registration number CRD420251034039. Graphical Abstract
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series BMC Geriatrics
spelling doaj-art-4a3558b00e2043d4b6a1923f52aa6ff82025-08-20T03:43:34ZengBMCBMC Geriatrics1471-23182025-07-0125112510.1186/s12877-025-06073-7Efficacy of music therapy as a non-pharmacological measure to support alzheimer's disease patients: a systematic reviewJia Wang0Cong Liu1Ying Dai2Can Mei3Guiping Wang4Yong Wang5Tao Huang6Jianbo Zhan7Jing Cheng8School of Public Health, Wuhan University of Science and TechnologyHubei Provincial Center for Disease Control and PreventionHubei Provincial Center for Disease Control and PreventionSchool of Public Health, Wuhan University of Science and TechnologySchool of Public Health, Wuhan University of Science and TechnologySchool of Public Health, Wuhan University of Science and TechnologyHuanggang City Center for Disease Control and Prevention, HuanggangHubei Provincial Center for Disease Control and PreventionSchool of Public Health, Wuhan University of Science and TechnologyAbstract Background Alzheimer's disease (AD) is a degenerative disease of the central nervous system characterized by progressive memory degradation and language and behavior disorders. Apart from curative pharmacological therapies, music therapy (MT) has been diffusely used as an efficient and economical non-pharmacological treatment for AD patients in recent years. Methods Three databases (PubMed, Web of Science and PsycINFO) were searched to analyse the efficacy of MT in patients with AD. Keywords included "Alzheimer's disease", "AD", "Mild Cognitive Impairment", "MCI", "music" and "music therapy". Results Literatures between January 2013 and January 2023 were selected, with 42 literatures included in the study, which highlights the beneficial impact of MT on cognition (memory, attention, language), behavioural and psychological symptoms (anxiety, depression and agitation), quality of life, self-esteem and physical pain in AD patients. Conclusion MT is a promising non-pharmacological treatment approach for individuals living with AD. However, further evidences from prospective, randomised, blinded, uniform, and rigorous method-logical investigations in this field are required to conclusively validate MT's impact on this disease. PROSPERO registration number CRD420251034039. Graphical Abstracthttps://doi.org/10.1186/s12877-025-06073-7Alzheimer's diseaseNon-pharmacological interventionMusic therapyCognitionSystematic review
spellingShingle Jia Wang
Cong Liu
Ying Dai
Can Mei
Guiping Wang
Yong Wang
Tao Huang
Jianbo Zhan
Jing Cheng
Efficacy of music therapy as a non-pharmacological measure to support alzheimer's disease patients: a systematic review
BMC Geriatrics
Alzheimer's disease
Non-pharmacological intervention
Music therapy
Cognition
Systematic review
title Efficacy of music therapy as a non-pharmacological measure to support alzheimer's disease patients: a systematic review
title_full Efficacy of music therapy as a non-pharmacological measure to support alzheimer's disease patients: a systematic review
title_fullStr Efficacy of music therapy as a non-pharmacological measure to support alzheimer's disease patients: a systematic review
title_full_unstemmed Efficacy of music therapy as a non-pharmacological measure to support alzheimer's disease patients: a systematic review
title_short Efficacy of music therapy as a non-pharmacological measure to support alzheimer's disease patients: a systematic review
title_sort efficacy of music therapy as a non pharmacological measure to support alzheimer s disease patients a systematic review
topic Alzheimer's disease
Non-pharmacological intervention
Music therapy
Cognition
Systematic review
url https://doi.org/10.1186/s12877-025-06073-7
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