Recent Developments Towards the Synthesis of Triazole Derivatives: A Review

Recent Developments Towards the Synthesis of Triazole Derivatives: A Review

The triazole scaffold is a crucial component of heterocyclic chemistry, serving as a basic building block in organic synthesis, materials science, and medicinal chemistry. Triazole is a five-membered ring composed of three nitrogen atoms and two carbon atoms, and it exists in two isomeric forms: 1,2...

Full description

Saved in:

Bibliographic Details
Main Authors:	Issam Ameziane El Hassani, Khouloud Rouzi, Anouar Ameziane El Hassani, Khalid Karrouchi, M’hammed Ansar
Format:	Article
Language:	English
Published:	MDPI AG 2024-10-01
Series:	Organics
Subjects:	heterocyclic 1,2,3-triazole 1,2,4-triazole microwave ultrasound green chemistry
Online Access:	https://www.mdpi.com/2673-401X/5/4/24
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Green ultrasound-assisted three-component click synthesis of novel 1H-1,2,3-triazole carrying benzothiazoles and fluorinated-1,2,4-triazole conjugates and their antimicrobial evaluation
by: Rezki Nadjet, et al.
Published: (2017-09-01)

Sulfur Derivatives of 1,2,4-Triazole: Recently Developed Compounds, Structure Activity Relationship, and Biological Activity: Review article
by: Azhar Mahdi Jasim, et al.
Published: (2024-12-01)

(4a<i>S</i>,5S,6a<i>R</i>,10a<i>R</i>,10b<i>R</i>)-5-Methoxy-9,9-dimethyl-4a,5,6a,7,10a,10b-hexahydro-12<i>H</i>-[1,3]dioxino[4′,5′:5,6]pyrano[4,3-b][1,2,3]triazolo[1,5-d][1,4]oxazine
by: Leticia Lomas Romero, et al.
Published: (2024-10-01)

Quinoline-thiosemicarbazone-1,2,3-triazole-acetamide derivatives as new potent α-glucosidase inhibitors
by: Aynaz Khademian, et al.
Published: (2024-12-01)

Novel hybrids of 1,2,3-triazole-benzoxazole: design, synthesis, and assessment of DprE1 enzyme inhibitors using fluorometric assay and computational analysis
by: Manisha Singh, et al.
Published: (2024-12-01)

In vitro Biological Evaluation of 1,2,4-triazole Mannich Base
by: Mahmood Sherzad Rafaat, et al.
Published: (2023-12-01)

Design, Synthesis, Characterization and antibacterial activity of new 1,2,3-triazole linked nucleosides
by: Aditya Aggarwal, et al.
Published: (2024-12-01)

Design and development of novel 1,2,3-triazole chalcone derivatives as potential anti-osteosarcoma agents via inhibition of PI3K/Akt/mTOR signalling pathway
by: Su Qing, et al.
Published: (2022-09-01)

Dual antioxidant and cytotoxic activities of novel 1,2,3-triazole-decorated unsymmetrical monocarbonyl curcumin analogs
by: Bayu Ardiansah, et al.
Published: (2025-06-01)

The research of pharmacokinetic parameters and metabolism of sodium 2-((4-amino-5-(thiophen-2-ylmethyl)-4h-1,2,4-triazol-3-yl)thio)acetate for use in military and civilian medicine
by: D. L. Usenko, et al.
Published: (2024-12-01)

Anti-cancer activity of synthetic gefitinib-1,2,3-triazole derivatives against Hela cells via induction of apoptosis
by: Zhihong Hu, et al.
Published: (2025-01-01)

Synthesis, crystal structure, Hirshfeld surface analysis, and DFT calculation of 4-(5-(((1-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazol-4-yl)methyl)thio)-4-phenyl-4H-1,2,4-triazol-3-yl)pyridine
by: Mohamed El-Naggar, et al.
Published: (2024-11-01)

Biological importance and synthesis of 1,2,3-triazole derivatives: a review
by: Mira J. Vaishnani, et al.
Published: (2024-12-01)

Synthesis, Characterisation, Theoretical NMR Calculations and Crystal Structure of the 3-methyl-1H-1,2,4?4-triazole-5-amine acetate
by: Patricia Saraiva Vilas Boas Almeida, et al.
Published: (2022-09-01)

Importance of the CuAAC Reaction in the Synthesis of Platinum Complexes with 1,4-Disubstituted-1<i>H</i>-1,2,3-triazoles: A Review of Their Anticancer Activity
by: Delia Hernández-Romero, et al.
Published: (2024-11-01)

Synthesis and characterization of some novel 1,2,4-triazoles, 1,3,4-thiadiazoles and Schiff bases incorporating imidazole moiety as potential antimicrobial agents
by: Aouad Mohamed Reda, et al.
Published: (2015-06-01)

Synthesis of Novel Gefitinib-Conjugated 1,2,3-Triazole Derivatives and Their Effect of Inducing DNA Damage and Apoptosis in Tumor Cells
by: Junfei Wu, et al.
Published: (2024-11-01)

Novel coumarin-based acetohydrazide-1,2,3-triazole derivatives as urease enzyme inhibitors: Synthesis, in vitro evaluation, and molecular dynamics simulation studies
by: Hassan Sepehrmansourie, et al.
Published: (2025-01-01)

Aldehyde Phenylamino-Pyrimidine as Key Precursor for the Synthesis of Imatinib Analogs and In Silico Studies of Their Intermediates
by: Luz E. Tierrablanca-Arias, et al.
Published: (2023-11-01)

Synthesis, biological screening, and in silico physicochemical analysis of novel 1,2,3-triazolyl oleate esters
by: Hilna Diana Sahaya, et al.
Published: (2024-12-01)

Search for New Compounds with Anti-Inflammatory Activity Among 1,2,4-Triazole Derivatives
by: Teresa Glomb, et al.
Published: (2024-12-01)

One-Pot Synthesis of Tetrazole–Triazole <i>Bis</i>-Heterocycles via Ugi–Azide Reaction
by: Fidel Rodriguez-Lopez, et al.
Published: (2023-11-01)

Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents
by: Xueqian Bai, et al.
Published: (2024-11-01)

An overview of the most used synthetic pathways of 1,2,4-triazolo[1,5-a]pyrimidines
by: Mohamed N. Zedan, et al.
Published: (2024-12-01)

Germanyl triazoles as a platform for CuAAC diversification and chemoselective orthogonal cross-coupling
by: John M. Halford-McGuff, et al.
Published: (2024-12-01)

Utilizing MEDT analysis of [3 + 2] cycloaddition reaction: x-ray crystallography of spirooxindole linked with thiophene/furan heterocycles and triazole framework
by: Abdulmajeed Abdullah Alayyaf, et al.
Published: (2024-11-01)

Design, synthesis, and anti-inflammatory activity of 2H-1,4-benzoxazin-3(4H)-one derivatives modified with 1,2,3-triazole in LPS-induced BV-2 cells
by: Xixi Hou, et al.
Published: (2025-01-01)

Synthesis, antifungal, antibacterial activity, and computational evaluations of some novel coumarin-1,2,4-triazole hybrid compounds
by: Maja Karnaš, et al.
Published: (2024-12-01)

Effects of 1<i>H</i>-1,2,3-Triazole Derivatives of 3-<i>O</i>-Acetyl-11-Keto-Beta-Boswellic Acid from <i>Boswellia sacra</i> Resin on T-Cell Proliferation and Activation
by: Abdo Meyiah, et al.
Published: (2024-12-01)

Exploring of N-phthalimide-linked 1,2,3-triazole analogues with promising anti-SARS-CoV-2 activity: synthesis, biological screening, and molecular modelling studies
by: Ateyatallah Aljuhani, et al.
Published: (2024-12-01)

Crystal structure of the 1:1 cocrystal 5,5′-(triaz-1-ene-1,3-diyl)bis(3-nitro-1H-1,2,4-triazole)–triethylammonium nitrate
by: Matthew Gettings, et al.
Published: (2024-12-01)

Synthesis and Antifungal Activity of Fmoc-Protected 1,2,4-Triazolyl-α-Amino Acids and Their Dipeptides Against <i>Aspergillus</i> Species
by: Tatevik Sargsyan, et al.
Published: (2025-01-01)

(<i>E</i>)-1-(3-(3-Hydroxy-4-Methoxyphenyl)-1-(3,4,5-Trimethoxyphenyl)allyl)-1<i>H</i>-1,2,4-Triazole and Related Compounds: Their Synthesis and Biological Evaluation as Novel Antimitotic Agents Targeting Breast Cancer
by: Gloria Ana, et al.
Published: (2025-01-01)

Design, Synthesis, enzyme inhibitory activity and molecular docking studies of new 1,2,3-triazole linked nucleobases
by: Aditya Aggarwal, et al.
Published: (2025-01-01)

Mechanistic Aspects of [3+2] Cycloaddition Reaction of Trifluoroacetonitrile with Diarylnitrilimines in Light of Molecular Electron Density Theory Quantum Chemical Study
by: Agnieszka Łapczuk, et al.
Published: (2024-12-01)

Design, Synthesis and Pharmacological Screening of β-Amino-, Thiadiazole/Thiadiazine-Phosphonate Based Triazole Motifs as Antimicrobial/Cytotoxic Agents
by: Abdou Wafaa M., et al.
Published: (2014-09-01)

Concomitant Inhibition and Collaring of Dual-Species Biofilms Formed by <i>Candida auris</i> and <i>Staphylococcus aureus</i> by Triazole Based Small Molecule Inhibitors
by: Humaira Parveen, et al.
Published: (2024-12-01)

Structure optimization and molecular dynamics studies of new tumor-selective s-triazines targeting DNA and MMP-10/13 for halting colorectal and secondary liver cancers
by: Christine A. Morcos, et al.
Published: (2024-12-01)

Design, synthesis, and apoptotic antiproliferative action of new 1,2,3-triazole/1,2,4-oxadiazole hybrids as dual EGFR/VEGFR-2 inhibitors
by: Mohamed A. Mahmoud, et al.
Published: (2024-12-01)

Ionic quaternary ammonium-triazole polymers as efficient single-component catalysts for CO2 conversion
by: Pobporn Promchan, et al.
Published: (2024-12-01)