Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 Vaccines

Cutaneous reactions following the COVID-19 vaccination, in particular mRNA vaccines, have been increasingly reported in literature. The most common morphologies were delayed large local reactions, local injection site reactions, urticaria, and morbilliform reaction. The purpose of this report is to...

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Main Authors: Milissa Makhlouf, Jennifer Akl, Alfred Ammoury
Format: Article
Language:English
Published: European Medical Journal 2021-04-01
Series:European Medical Journal
Online Access:https://www.emjreviews.com/dermatology/article/varicella-zoster-reactivation-following-mrna-vaccination-two-case-reports-and-a-review-of-cutaneous-adverse-events-of-covid-19-vaccines/
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author Milissa Makhlouf
Jennifer Akl
Alfred Ammoury
author_facet Milissa Makhlouf
Jennifer Akl
Alfred Ammoury
author_sort Milissa Makhlouf
collection DOAJ
description Cutaneous reactions following the COVID-19 vaccination, in particular mRNA vaccines, have been increasingly reported in literature. The most common morphologies were delayed large local reactions, local injection site reactions, urticaria, and morbilliform reaction. The purpose of this report is to review the cutaneous manifestations of COVID-19 vaccines and to report two cases of COVID-19 mRNA vaccine-induced varicella zoster reactivation along with the possible pathogenesis. These two cases are of an 80-year-old female patient with multiple comorbidities and a previously healthy 57-year-old male patient who experienced varicella zoster reactivation post-COVID-19 mRNA vaccine (Pfizer, New York City, New York, USA) following the first and second dose
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issn 2397-6764
language English
publishDate 2021-04-01
publisher European Medical Journal
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series European Medical Journal
spelling doaj-art-4a098fad587c4c2e9820e833987db60c2025-01-16T16:57:16ZengEuropean Medical JournalEuropean Medical Journal2397-67642021-04-0110.33590/emj/21-00254Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 VaccinesMilissa Makhlouf0Jennifer Akl1Alfred Ammoury2Department of Dermatology, Saint George Hospital University Medical Center, Beirut, Lebanon; Faculty of Medicine, University of Balamand, LebanonDepartment of Dermatology, Saint George Hospital University Medical Center, Beirut, Lebanon; Faculty of Medicine, University of Balamand, LebanonDepartment of Dermatology, Saint George Hospital University Medical Center, Beirut, Lebanon; Faculty of Medicine, University of Balamand, Lebanon Cutaneous reactions following the COVID-19 vaccination, in particular mRNA vaccines, have been increasingly reported in literature. The most common morphologies were delayed large local reactions, local injection site reactions, urticaria, and morbilliform reaction. The purpose of this report is to review the cutaneous manifestations of COVID-19 vaccines and to report two cases of COVID-19 mRNA vaccine-induced varicella zoster reactivation along with the possible pathogenesis. These two cases are of an 80-year-old female patient with multiple comorbidities and a previously healthy 57-year-old male patient who experienced varicella zoster reactivation post-COVID-19 mRNA vaccine (Pfizer, New York City, New York, USA) following the first and second dosehttps://www.emjreviews.com/dermatology/article/varicella-zoster-reactivation-following-mrna-vaccination-two-case-reports-and-a-review-of-cutaneous-adverse-events-of-covid-19-vaccines/
spellingShingle Milissa Makhlouf
Jennifer Akl
Alfred Ammoury
Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 Vaccines
European Medical Journal
title Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 Vaccines
title_full Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 Vaccines
title_fullStr Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 Vaccines
title_full_unstemmed Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 Vaccines
title_short Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 Vaccines
title_sort varicella zoster reactivation following mrna vaccination two case reports and a review of cutaneous adverse events of covid 19 vaccines
url https://www.emjreviews.com/dermatology/article/varicella-zoster-reactivation-following-mrna-vaccination-two-case-reports-and-a-review-of-cutaneous-adverse-events-of-covid-19-vaccines/
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