The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change

Abstract Changes in diet causing ecological stress pose a significant challenge to animal survival. In response, the gut microbiota, a crucial part of the host’s digestive system, exhibits patterns of change reflective of alterations in the host’s food component. The impact of temporal dietary shift...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuhang Li, Yujie Yan, Haojie Wu, Yiyi Men, Yi Yang, Hengguang Fu, Derek Dunn, Xiaowei Wang, Genggeng Gao, Peng Zhang, Guixin Dong, Liyuan Hao, Jia Jia, Baoguo Li, Songtao Guo
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Animal Microbiome
Subjects:
Online Access:https://doi.org/10.1186/s42523-024-00349-w
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846171589259821056
author Yuhang Li
Yujie Yan
Haojie Wu
Yiyi Men
Yi Yang
Hengguang Fu
Derek Dunn
Xiaowei Wang
Genggeng Gao
Peng Zhang
Guixin Dong
Liyuan Hao
Jia Jia
Baoguo Li
Songtao Guo
author_facet Yuhang Li
Yujie Yan
Haojie Wu
Yiyi Men
Yi Yang
Hengguang Fu
Derek Dunn
Xiaowei Wang
Genggeng Gao
Peng Zhang
Guixin Dong
Liyuan Hao
Jia Jia
Baoguo Li
Songtao Guo
author_sort Yuhang Li
collection DOAJ
description Abstract Changes in diet causing ecological stress pose a significant challenge to animal survival. In response, the gut microbiota, a crucial part of the host’s digestive system, exhibits patterns of change reflective of alterations in the host’s food component. The impact of temporal dietary shifts on gut microbiota has been elucidated through multidimensional modeling of both food component and macronutrient intake. However, the broad distribution of wild generalist and the intricate complexity of their food component hinder our capacity to ascertain the degree to which their gut microbiota assist in adapting to spatial dietary variations. We examined variation in patterns of the gut microbial community according to changes in diet and in a colobine monkey with a regional variable diet, the golden snub-nosed monkey (Rhinopithecus roxellana). Specifically, we analyse the interactions between variation in food component, macronutrient intake and the gut microbial community. We compared monkeys from four populations by quantifying food component and macronutrient intake, and by sequencing 16S rRNA and the microbial macro-genomes from the faecal samples of 44 individuals. We found significant differences in the diets and gut microbial compositions, in nutrient space and macronutrient intake among some populations. Variations in gut microbiota composition across distinct populations mirror the disparities in macronutrient intake, with a notable emphasis on carbohydrate. Geographical differences in the diet among of golden snub-nosed monkey populations will result in macronutrient intake variation, with corresponding differences in macronutrient intake driving regional differences in the compositions and abundances of gut microbiota. Importantly, the gut microbiota associated with core digestive functions does not vary, with the non-core gut microbiota fluctuating in response to variation in macronutrient intake. This characteristic may enable species heavily reliant on gut microbiota for digestion to adapt to diet changes. Our results further the understanding of the roles gut microbiota play in the formation of host dietary niches.
format Article
id doaj-art-49f201891f3e46a5b0dc8f5a06b66de9
institution Kabale University
issn 2524-4671
language English
publishDate 2024-11-01
publisher BMC
record_format Article
series Animal Microbiome
spelling doaj-art-49f201891f3e46a5b0dc8f5a06b66de92024-11-10T12:44:12ZengBMCAnimal Microbiome2524-46712024-11-016111310.1186/s42523-024-00349-wThe role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet changeYuhang Li0Yujie Yan1Haojie Wu2Yiyi Men3Yi Yang4Hengguang Fu5Derek Dunn6Xiaowei Wang7Genggeng Gao8Peng Zhang9Guixin Dong10Liyuan Hao11Jia Jia12Baoguo Li13Songtao Guo14Shaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityShaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityShaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityShaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityShaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityInstitute of Zoology, Chinese Academy of SciencesShaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityShaanxi Key Laboratory for Animal Conservation, Institute of Zoology, Shaanxi Academy of SciencesResearch Center for the Qinling Giant Panda (Shaanxi Rare Wildlife Rescue Base)Chimelong Group Co.Chimelong Group Co.Shaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityShaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityShaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityShaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest UniversityAbstract Changes in diet causing ecological stress pose a significant challenge to animal survival. In response, the gut microbiota, a crucial part of the host’s digestive system, exhibits patterns of change reflective of alterations in the host’s food component. The impact of temporal dietary shifts on gut microbiota has been elucidated through multidimensional modeling of both food component and macronutrient intake. However, the broad distribution of wild generalist and the intricate complexity of their food component hinder our capacity to ascertain the degree to which their gut microbiota assist in adapting to spatial dietary variations. We examined variation in patterns of the gut microbial community according to changes in diet and in a colobine monkey with a regional variable diet, the golden snub-nosed monkey (Rhinopithecus roxellana). Specifically, we analyse the interactions between variation in food component, macronutrient intake and the gut microbial community. We compared monkeys from four populations by quantifying food component and macronutrient intake, and by sequencing 16S rRNA and the microbial macro-genomes from the faecal samples of 44 individuals. We found significant differences in the diets and gut microbial compositions, in nutrient space and macronutrient intake among some populations. Variations in gut microbiota composition across distinct populations mirror the disparities in macronutrient intake, with a notable emphasis on carbohydrate. Geographical differences in the diet among of golden snub-nosed monkey populations will result in macronutrient intake variation, with corresponding differences in macronutrient intake driving regional differences in the compositions and abundances of gut microbiota. Importantly, the gut microbiota associated with core digestive functions does not vary, with the non-core gut microbiota fluctuating in response to variation in macronutrient intake. This characteristic may enable species heavily reliant on gut microbiota for digestion to adapt to diet changes. Our results further the understanding of the roles gut microbiota play in the formation of host dietary niches.https://doi.org/10.1186/s42523-024-00349-wMacronutrient intakeDietary nichesGut microbiotaWeighted gene co-expression networkPrimate
spellingShingle Yuhang Li
Yujie Yan
Haojie Wu
Yiyi Men
Yi Yang
Hengguang Fu
Derek Dunn
Xiaowei Wang
Genggeng Gao
Peng Zhang
Guixin Dong
Liyuan Hao
Jia Jia
Baoguo Li
Songtao Guo
The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change
Animal Microbiome
Macronutrient intake
Dietary niches
Gut microbiota
Weighted gene co-expression network
Primate
title The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change
title_full The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change
title_fullStr The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change
title_full_unstemmed The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change
title_short The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change
title_sort role of gut microbiota in a generalist golden snub nosed monkey adaptation to geographical diet change
topic Macronutrient intake
Dietary niches
Gut microbiota
Weighted gene co-expression network
Primate
url https://doi.org/10.1186/s42523-024-00349-w
work_keys_str_mv AT yuhangli theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT yujieyan theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT haojiewu theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT yiyimen theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT yiyang theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT hengguangfu theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT derekdunn theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT xiaoweiwang theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT genggenggao theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT pengzhang theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT guixindong theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT liyuanhao theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT jiajia theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT baoguoli theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT songtaoguo theroleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT yuhangli roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT yujieyan roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT haojiewu roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT yiyimen roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT yiyang roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT hengguangfu roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT derekdunn roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT xiaoweiwang roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT genggenggao roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT pengzhang roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT guixindong roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT liyuanhao roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT jiajia roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT baoguoli roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange
AT songtaoguo roleofgutmicrobiotainageneralistgoldensnubnosedmonkeyadaptationtogeographicaldietchange